Sulfated modification, characterization and structure-antioxidant relationships of Artemisia sphaerocephala polysaccharides
Sulfated modification, characterization and structure-antioxidant relationships of Artemisia sphaerocephala polysaccharides
复制标题
白蒿多糖的硫酸化修饰、表征及其结构-抗氧化关系
DOI：
10.1016/j.carbpol.2010.04.002
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发表时间：
2010-07-23
影响因子：
11.2
通讯作者：
Wang, Yunpu
中科院分区：
文献类型：
--
作者：
Wang, Junlong;Guo, Hongyun;Wang, Yunpu
Sulfated polysaccharides exerted potent biological property which was relative to degree of sulfation (DS). M. substitution position and chain conformation. In the present study, sulfated derivatives of Artemisia sphaerocephala polysaccharide (ASP) with different DS were synthesized by chlorosulfuric acid/pyridine method. FT-IR and C-13 NMR analysis indicated that C-6 substitution was predominant in sulfated ASP (SASP) compared with other positions at C-2. In the sulfation reaction, a sharp decrease in M-w was observed in SASP. The d(f) values from 1.96 to 2.77 indicated that the -SO3H groups leading to the relatively expanded conformation of SASP. Antioxidant assays showed that SASP had better antioxidant activities. The data obtained in vitro models indicated that high DS and moderate M showed the best antioxidant capacities. Crown Copyright (C) 2010 Published by Elsevier Ltd. All rights reserved.
