Prediction of visual field deficits by diffusion tensor imaging in temporal lobe epilepsy surgery
Prediction of visual field deficits by diffusion tensor imaging in temporal lobe epilepsy surgery
复制标题
颞叶癫痫手术中弥散张量成像预测视野缺损
DOI：
10.1016/j.neuroimage.2008.11.038
复制
发表时间：
2009-04-01
期刊：
影响因子：
5.7
通讯作者：
Nimsky, Christopher
中科院分区：
文献类型：
--
作者：
Chen, Xiaolei;Weigel, Daniel;Nimsky, Christopher
视神经放射性损伤所致的视野缺损是癫痫颞叶切除术的常见并发症。在这项前瞻性研究中，基于弥散张量成像（DTI）的纤维跟踪进行了48例患者的颞叶切除术的药物抵抗性癫痫。术前和术中均采用DTI纤维追踪技术观察视神经放射情况，预测术后视野缺损。利用DTI技术的光纤跟踪技术可以成功地重建出光辐射的过程。术后视野缺损的结果与纤维追踪估计值有显著相关性。受试者工作特征（ROC）曲线分析证实了术前和术中纤维跟踪结果预测术后视野缺损的准确性和有效性。术中视觉辐射的可视化可能有助于避免术后视野缺损。(c)2008年爱思唯尔公司All rights reserved.
Visual field deficits due to optic radiation injury are a common complication of temporal lobectomy in epilepsy surgery. In this prospective study, diffusion tensor imaging (DTI) based fiber tracking was performed on 48 patients who had temporal lobectomy for pharmaco-resistant epilepsy. Pre- and intra-operative DTI based fiber tracking was used to visualize the optic radiation and to predict the post-operative visual field defects. The course of the optic radiation could be successfully reconstructed by DTI based fiber tracking. There was a significant correlation between the fiber tracking estimation and the outcome of visual field deficits after surgery. The Receiver Operating Characteristic (ROC) curve analysis confirmed the accuracy and validity of prediction of the post-operative visual field deficits comparing pre- and intra-operative fiber tracking results. Intra-operative visualization of the optic radiation may help in avoiding post-operative visual field deficits. (c) 2008 Elsevier Inc. All rights reserved.