Human T lymphocyte subsets. Functional heterogeneity and surface recognition structures.
Human T lymphocyte subsets. Functional heterogeneity and surface recognition structures.
复制标题
人类 T 淋巴细胞亚群。
DOI：
10.1172/jci111571
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
Schlossman,SF
中科院分区：
文献类型：
--
作者：
Romain,PL;Schlossman,SF
T淋巴细胞的分化。胸腺微环境对于早期T细胞分化是必需的。大多数淋巴细胞祖细胞迁移到胸腺发生在胚胎期和出生后早期（9-12）。这些细胞经过处理，变得有功能，然后输出到外周淋巴区室，尽管只有一部分进入胸腺的细胞最终在外周淋巴组织和循环中可检测到。此外，胸腺上皮可能具有
Differentiation of T lymphocytes. The thymic micro-environment is necessary for early T cell differentiation. Most of the migration of lymphocyte progenitors to the thymus takes place during embryonic and early postnatal life (9-12). These cells are processed, become functionally competent, and are then exported into the peripheral lymphoid compartments, although only a fraction of the cells which enter the thymus are eventually detectable in the peripheral lymphoid tissues and circulation. In addition, the thymicepithelium may have