NATURAL HISTORY OF LUPUS ERYTHEMATOSUS DISSEMINATUS
NATURAL HISTORY OF LUPUS ERYTHEMATOSUS DISSEMINATUS
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DOI：
10.7326/0003-4819-38-4-717
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发表时间：
1953-01-01
影响因子：
39.2
通讯作者：
RAGAN, C
中科院分区：
文献类型：
--
作者：
JESSAR, RA;LAMONTHAVERS, RW;RAGAN, C
在一组44例观察患者和279例从文献中获得的播散性红斑狼疮的自然史进行了研究，以确定疾病的预期病程，而无需使用有效的抗炎药。在诊断中使用的标准进行了概述。临床和实验室的特点，并在17例尸检结果进行了讨论。评估疾病的持续时间和病程。虽然预后不佳，但超过20%的患者仍存活超过5年。使用强效消炎药似乎并没有改变预期的死亡率。
The natural history of lupus erythematosus disseminatus was studied in a group of 44 observed patients and 279 obtained from the literature to determine the expected course of the disease without the therapeutic use of potent antiphlogistic agents. The criteria used in diagnosis are outlined. The clinical and laboratory features are presented and autopsy findings in 17 patients are discussed. The duration and course of the disease are evaluated. While the prognosis is unfavorable, over 20% remain alive for periods in excess of five years. Use of potent antiphlogistic therapeutic agents does not seem to have changed this expected mortality.