Serologic Responses to the Mallein Test for Glanders in Solipeds
Serologic Responses to the Mallein Test for Glanders in Solipeds
复制标题
独足类鼻疽马林氏试验的血清学反应
DOI：
10.1177/104063879300500121
复制
发表时间：
1993
影响因子：
1.5
通讯作者：
D. P. Olson
中科院分区：
文献类型：
--
作者：
Joyce M. Hagebock;L. Schlater;W. M. Frerichs;D. P. Olson
uolation in DRG, as seen in this horse, is a feature of some cases of rabies and spongiform change, beginning as vacuolation principally in dendrites, is a significant aspect of the histopathology of rabies. Direct FA examination is regarded as the best available test for a rapid and specific diagnosis of rabies. In this case, the brain was FA negative, probably because only hippocampus, and not brain stem, was examined. Brain stem and cerebellum provide the best diagnostic tissues for direct FA testing of livestock. 16 Diagnosis was achieved by immunocytochemistry, a method of growing importance in both research and diagnostic aspects of rabies. Mouse inoculation continues to be an important method for confirmation of a diagnosis of rabies, with a detection rate of 95%. Rabies immunocytochemical examination of formalin-fixed tissue can be as sensitive as FA, with the advantage that it can be used when the only tissue available is formalin or glutaraldehyde fixed or when autolysis, which compromises both FA examination and attempted virus isolation in cell culture, is present. Acknowledgements. We appreciate the confirmation of rabies in this case by Dr. D. M. Haines and the immunocytochemistry unit at the Western College of Veterinary Medicine, Saskatoon, Saskatchewan, Canada, using an ABC technique. We thank Mary Benson for typing the manuscript.
