Babesia parasites develop and are transmitted by the non-vector soft tick Ornithodoros moubata (Acari: Argasidae)
Babesia parasites develop and are transmitted by the non-vector soft tick Ornithodoros moubata (Acari: Argasidae)
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DOI：
10.1017/s0031182006000916
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发表时间：
2007-01-01
期刊：
影响因子：
2.4
通讯作者：
Fujisaki, K.
中科院分区：
文献类型：
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作者：
Battsetseg, B.;Matsuo, T.;Fujisaki, K.
毛氏捕鸟蜱以感染马巴贝虫的血液为食。然而，如B的消失所证明的，寄生虫很快被清除。来自蜱虫的等特异性核糖体RNA。我们假设，如果巴氏疟原虫可以逃脱中肠相关的障碍，非媒介蜱可以感染巴氏疟原虫。为了验证这一假设，B.等。将来自体外培养的寄生虫感染的血液注射到蜱的血腔中。B。在注射后45天甚至在卵中也令人惊讶地检测到等特异性rRNA。无巴贝西亚的狗感染O。通过接种B感染的Moubata蜱。吉布森感染的红细胞寄生虫血症和抗B的Bg-TRAP抗体产生。Gibsoni逐渐增加。这些结果表明O. moubata是一种有效的巴氏疟原虫病媒模型，也是研究蜱对巴氏疟原虫免疫和蜱-巴氏疟原虫相互作用的重要工具。
Ornithodoros moubata ticks were fed on blood infected with Babesia equi. However, the parasites were quickly cleared as evidenced by the disappearance of B. equi-specific ribosomal RNA from the ticks. We hypothesized that if the Babesia parasite can escape midgut-associated barriers a non-vector tick can become infected with Babesia. To test this hypothesis, B. equi. parasite-infected blood from in vitro culture was injected into the haemocoel of ticks. B. equi-specific rRNA was surprisingly detected 45 days after injection even in the eggs. Babesia-free dogs were infested with O. Moubata ticks that were infected by inoculation with B. gibsoni-infected red blood cells. Parasitaemia and antibody production against Bg-TRAP of B. gibsoni increased gradually. These results indicate that O. moubata may be a useful vector model for Babesia parasites and also a very important tool for studies on tick immunity against Babesia parasites and tick-Babesia interactions.