Myocardial blood capillary reaction in various forms of cardiac hypertrophy
Myocardial blood capillary reaction in various forms of cardiac hypertrophy
复制标题
各种形式心脏肥大的心肌毛细血管反应
DOI：
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发表时间：
1972
期刊：
影响因子：
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通讯作者：
Arne Ljungqvist
中科院分区：
文献类型：
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作者：
E. Mandache;G. Unge;Arne Ljungqvist
摘要： 研究了大鼠运动（游泳）致心脏肥大和主动脉瓣狭窄时心肌毛细血管反应的超微结构。在游泳运动的大鼠的心脏中获得了毛细血管新生的明确证据，而在主动脉瓣狭窄的大鼠的心脏中没有观察到毛细血管反应。生长的毛细血管首先以间质中周细胞样细胞的实心索出现。在这些索带的中央核心出现裂缝，其内衬有含有胞饮小泡的内皮样细胞。这些细胞可能是转化的周细胞，也可能是沿着脊髓内部的内皮增殖的结果。当裂口与原始毛细血管腔建立接触时，它扩大以形成该腔的延续。
SummaryThe ultrastructure of the myocardial blood capillary reaction in cardiac hypertrophy induced by physical exercise (swimming) and aortic stenosis was studied in the rat. Clear evidence of a neoformation of capillaries was obtained in the hearts of the swimming exercised rats, whereas no capillary reaction was observed in the hearts from rats with aortic stenosis. The growing capillaries first appeared as solid cords of pericyte-like cells in the interstitium. In the central core of these cords clefts appeared which were lined by endothelial-like cells containing pinocytotic vesicles. These cells might either be transformed pericytes or the result of endothelial proliferation along the interior of the cord. When the cleft established contact with the original capillary lumen it enlarged to form a continuation of this lumen.