Technical aspects of MR perfusion
Technical aspects of MR perfusion
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DOI：
10.1016/j.ejrad.2010.02.017
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发表时间：
2010-12-01
影响因子：
3.3
通讯作者：
Sourbron, Steven
中科院分区：
文献类型：
--
作者：
Sourbron, Steven
用MRI测量灌注的最常见方法是动脉自旋标记（ASL）、动态磁敏感对比（DSC-MRI）和T-1加权动态对比增强（DCE-MRI）。本文重点介绍后一种方法，这是迄今为止最常见的在身体和生产措施的毛细血管通透性以及。目的是提出一个简洁而完整的概述DCE-MRI数据采集和分析所涉及的技术问题。详细情况请读者参阅参考文献。该主题的介绍基本上是通用的，重点是所有DCE-MRI测量的共同技术方面。对于器官特定的问题和插图，我们参考了本期的其他论文。在第1节“理论”中，定义了基本量，并提出了提供血液动力学参数和DCE-MRI信号之间关系的物理机制。第2节“数据采集”讨论了最佳测量协议设计中涉及的问题。第3节“数据分析”总结了根据测量数据确定血流动力学参数所需采取的步骤。(C)2010爱思唯尔爱尔兰有限公司版权所有。
The most common methods for measuring perfusion with MRI are arterial spin labelling (ASL), dynamic susceptibility contrast (DSC-MRI), and T-1-weighted dynamic contrast enhancement (DCE-MRI). This review focuses on the latter approach, which is by far the most common in the body and produces measures of capillary permeability as well.The aim is to present a concise but complete overview of the technical issues involved in DCE-MRI data acquisition and analysis. For details the reader is referred to the references. The presentation of the topic is essentially generic and focuses on technical aspects that are common to all DCE-MRI measurements. For organ-specific problems and illustrations, we refer to the other papers in this issue.In Section 1 "Theory" the basic quantities are defined, and the physical mechanisms are presented that provide a relation between the hemodynamic parameters and the DCE-MRI signal. Section 2 "Data acquisition" discusses the issues involved in the design of an optimal measurement protocol. Section 3 "Data analysis" summarizes the steps that need to be taken to determine the hemodynamic parameters from the measured data. (C) 2010 Elsevier Ireland Ltd. All rights reserved.