Serum antioxidant micronutrient levels in oral lichen planus
Serum antioxidant micronutrient levels in oral lichen planus
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DOI：
10.1034/j.1600-0714.2001.300502.x
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发表时间：
2001-05-01
影响因子：
3.3
通讯作者：
Ito, Y
中科院分区：
文献类型：
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作者：
Nagao, T;Warnakulasuriya, S;Ito, Y
本研究的目的是通过一项以人群为基础的病例对照研究来阐明口腔扁平苔藓（OLP）与血清抗氧化微量营养素之间的任何关联。共有9536名受试者进行了检查，62名（58名网状，4名萎缩性和糜烂性）在转诊机构诊断为OLP，与年龄和性别匹配的无病受试者中选择的每例（n=248）对照进行了比较。血清微量营养素（视黄醇、α-生育酚、玉米黄质/叶黄素和隐黄质、番茄红素、α-胡萝卜素和β-胡萝卜素）的水平通过高效液相色谱（HPLC）法来估计。病例组血清视黄醇水平（2.820 ± 0.849 μ mol/l）显著高于对照组（2.562 ± 0.735 μ mol/l）（P
The aim of this study was to elucidate any association between oral lichen planus (OLP) and serum antioxidant micronutrients by a population-based case-control study. A total of 9536 subjects were examined, and 62 (58 reticular, 4 atrophic and erosive) diagnosed with OLP at referral facilities were compared with four controls per case (n=248) selected among disease-free subjects matched for age and sex. Serum levels of micronutrients (retinol, alpha -tocopherol, zeaxanthin/lutein and cryptoxanthin, lycopene, alpha -carotene and beta -carotene) were estimated by the high performence liquid chromatography (HPLC) method. Among cases, mean serum retinol level (2.820 +/-0.849 mu mol/l) was significantly higher compared with that of controls (2.562 +/-0.735 mu mol/l) (P