SARCOPENIA AND AGE-RELATED-CHANGES IN BODY-COMPOSITION AND FUNCTIONAL-CAPACITY

SARCOPENIA AND AGE-RELATED-CHANGES IN BODY-COMPOSITION AND FUNCTIONAL-CAPACITY
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DOI:
10.1093/jn/123.suppl_2.465
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发表时间:
1993-02-01
影响因子:
4.2
通讯作者:
CAMPBELL, WW
CAMPBELL, WW
中科院分区:
医学2区
文献类型:
--
作者:
EVANS, WJ;CAMPBELL, WW

文献摘要

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成年年龄的增长与身体成分的深刻变化有关。这些变化中最突出的一个是肌肉减少症,定义为骨骼肌质量的年龄相关性损失,这导致力量和有氧能力下降,从而导致功能能力下降。肌肉减少症也与年龄相关的骨矿物质、基础代谢率和体脂含量增加的损失密切相关。通过体育锻炼和训练,特别是阻力训练,可以预防肌肉减少症和一系列显著的相关异常,如II型糖尿病、冠状动脉疾病、高血压、骨质疏松症和肥胖症。使用足够的频率,强度和持续时间的锻炼计划,在任何年龄都很可能增加肌肉力量和耐力。没有任何药物干预比运动更有希望改善老年人的健康和促进老年人的独立性。
Advancing adult age is associated with profound changes in body composition. One of the most prominent of these changes is sarcopenia, defined as the age-related loss in skeletal muscle mass, which results in decreased strength and aerobic capacity and thus functional capacity. Sarcopenia is also closely linked to age-related losses in bone mineral, basal metabolic rate and increased body fat content. Through physical exercise and training, especially resistance training, it may be possible to prevent sarcopenia and the remarkable array of associated abnormalities, such as type II diabetes, coronary artery disease, hypertension, osteoporosis and obesity. Using an exercise program of sufficient frequency, intensity and duration, it is quite possible to increase muscle strength and endurance at any age. There is no pharmacological intervention that holds a greater promise of improving health and promoting independence in the elderly than does exercise.