Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics
Black Phosphorus Nanosheets as a Robust Delivery Platform for Cancer Theranostics
复制标题
黑磷纳米片作为癌症治疗诊断学的强大传递平台。
DOI：
10.1002/adma.201603276
复制
发表时间：
2017-01-04
影响因子：
29.4
通讯作者：
Mei, Lin
中科院分区：
文献类型：
--
作者：
Tao, Wei;Zhu, Xianbing;Mei, Lin
二维黑磷（BP）纳米材料作为一个交付平台。首次揭示了聚乙二醇化BP纳米片在癌细胞中的内吞途径和生物活性。最后，通过聚乙二醇化BP纳米片实现了三重应答的联合治疗策略，显示出有希望的和增强的抗肿瘤作用。
2D black phosphorus (BP) nano-materials are presented as a delivery platform. The endocytosis pathways and biological activities of PEGylated BP nanosheets in cancer cells are revealed for the first time. Finally, a triple-response combined therapy strategy is achieved by PEGylated BP nanosheets, showing a promising and enhanced antitumor effect.