Chromatography
Chromatography
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DOI：
10.1111/j.2042-7158.1949.tb12474.x
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发表时间：
1949-09
影响因子：
3.3
通讯作者：
中科院分区：
文献类型：
--
作者：
在这些化合物已被解毒或消除之后，从Pagc 63.0中移除。增强作用是由于砜致敏作用和标准饮食中新鲜蔬菜中的某些元素（新鲜卷心菜、特氟沙星、长效制剂）的联合作用。E. C a r I in f a n t i，F. D'A 1 B和L.我也是。（Lancer，1949，第256页，第379页）向lg. 10毫升的结晶睾酮酒精（96%）在持续搅拌下缓慢加入70 ml。磷酸铝的水悬浮液7 mg/ml。ml.使混合物沉淀并倾析出上清液。将残留物补足至30 ml。盐水溶液。该制剂稳定，可用细针给药。实验在去势豚鼠上进行，一组接受一次剂量为25 mg/kg的丙酸睾丸酮油溶液注射。100克，而另一组则是等量的纯净水。睾酮吸附在磷酸铝上。结果发现，一次注射油包酯制剂导致精囊重量迅速上升和下降，而新制剂产生更大和更持续的作用，达到峰值而不是更早。S. L . W.给药后311天。S. L. W.
S (Corrrirrrrrtl from Pagc 63.0 tl:iys after these compounds have been detoxicated or eliminated. The potentiating effect is due to the combined effect of the sulphone sensitisation and some element in fresh vegetables in the standard diet (fresh cabbage, Testosterone, Long-Acting Preparation of. E. C a r I i n f a n t i, F. D'A 1 b and L. C u t o lo. (Lancer, 1949, 256, 379.) To a solution of 1 g. of crystalline testosterone in 10 ml. of alcohol (96 per cent.) is slowly added, with constant stirring, 70 ml. of a n equeous suspension of aluminium phosphate 7 mg./ml. The mixture is allowed to sediment and the supernatant fluid decanted off. The residue is made up to 30 ml. with saline solution. The preparation is stable and can be administered with a fine needle. Experiments were carried out on castrated guinea-pigs, one group receiving one injection o f testosterone propionate in oil in a dose of 25 mg./ 100 g., and another group the same amount of pure. testosterone adsorbed on to aluminium phosphate. It was found that one injection of the ester-in-oil preparation leads to a rapid rise and fall in t,he weight of the seminal vesicles, whereas the new preparation produc'es a greater and more continuous action, reaching a peak not earlier 637 lettuce, carrots, hay and oats). s. L . w. than 311 days after administration. s. L. w.