Self-reported sleep duration as a predictor of all-cause mortality: results from the JACC study, Japan.

Self-reported sleep duration as a predictor of all-cause mortality: results from the JACC study, Japan.
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DOI:
10.1093/sleep/27.1.51
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发表时间:
2004-02
期刊:
影响因子:
5.6
通讯作者:
A. Tamakoshi;Y. Ohno
A. Tamakoshi;Y. Ohno
中科院分区:
医学2区
文献类型:
--
作者:
A. Tamakoshi;Y. Ohno

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流行病学研究表明,习惯性睡眠模式与全因死亡风险相关。然而,睡眠时间可能会受到身体,精神或社会条件的影响,其对健康的影响可能因时间或地点而异。在调整了几个协变量,特别是精神状况后,研究睡眠时间对全因死亡率的影响。方法1988 ~ 1990年参加日本癌症风险评估协作队列研究(JACC Study on Evaluation of Cancer Risk,Japan Collaborative Cohort Study on Evaluation of Cancer Risk,Monbusho)的40 ~ 79岁的104,010例受试者(男性43,852例,女性60,158例),平均随访9.9年。分析中使用了工作日的平均睡眠时间和协变量,包括感知的精神压力和抑郁症状。采用考克斯比例风险模型分别按性别计算相对危险度。结果男性睡眠时间比女性长,老年人睡眠时间比年轻人长。男性平均睡眠时间为7.5小时,女性为7.1小时;模式持续时间分别为8小时(范围,7.5-8.4小时)和7小时(6.5-7.4小时)。睡眠时间短于或长于7小时与全因死亡风险显著升高相关。然而,当对男性中的一些协变量进行调整时,与短睡眠的显著关联消失了。结论:夜间睡眠时间为7小时的人死亡风险最低。
BACKGROUND Epidemiologic studies have shown that habitual sleeping patterns are associated with all-cause mortality risk. However, sleep duration may be affected by physical, mental, or social conditions, and its impact on health may differ depending on the time or place. OBJECTIVES To examine the effects of sleep duration on all-cause mortality after adjusting for several covariates, mental condition in particular. METHODS A total of 104,010 subjects (43,852 men and 60,158 women), aged 40 to 79 years, who enrolled in the JACC Study (Japan Collaborative Cohort Study on Evaluation of Cancer Risk Sponsored by Monbusho) from 1988 to 1990 and were followed for an average of 9.9 years. Average sleep duration on weekdays and covariates, including perceived mental stress and depressive symptoms, were used in the analyses. Relative risks were calculated by Cox's proportional hazard model separately by sex. RESULTS Men tended to sleep longer than women, and the elderly slept longer than younger subjects. Mean sleep duration was 7.5 hours for men and 7.1 hours for women; mode durations were 8 hours (range, 7.5-8.4 hours) and 7 hours (6.5-7.4), respectively. Sleep duration of shorter or longer than 7 hours was associated with a significantly elevated risk of all-cause mortality. However, the significant association with short sleep disappears when adjusted for some covariates among men. CONCLUSIONS Sleep duration at night of 7 hours was found to show the lowest mortality risk.