Non-Newtonian blood flow in human right coronary arteries: Transient simulations

Non-Newtonian blood flow in human right coronary arteries: Transient simulations
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DOI:
10.1016/j.jbiomech.2005.01.034
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发表时间:
2006-01-01
影响因子:
2.4
通讯作者:
Kilpatrick, D
Kilpatrick, D
中科院分区:
工程技术3区
文献类型:
--
作者:
Johnston, BM;Johnston, PR;Kilpatrick, D

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这项研究着眼于通过四个不同的右冠状动脉,这已经从双平面血管造影重建的脉动血流。一个非牛顿的血液模型(广义幂律),以及通常的牛顿模型的血液粘度,是用来研究在每个这些动脉在整个心动周期的壁剪切应力。牛顿和非牛顿血液模型之间的差异也研究了在整个心动周期使用最近广义的全球非牛顿的重要性因素。此外,考虑无质量粒子的路径引入到流场的流动进行了研究,研究表明,在研究动脉中的瞬态血液流动的壁面剪应力分布时,使用牛顿血液模型是一个合理的好的近似。然而,为了更详细地研究动脉内的流动,非牛顿模型更合适。(c)2005爱思唯尔有限公司保留所有权利。
This study looks at pulsatile blood flow through four different right coronary arteries, which have been reconstructed from biplane angiograms. A non-Newtonian blood model (the Generalised Power Law), as well as the usual Newtonian model of blood viscosity, is used to study the wall shear stress in each of these arteries over the entire cardiac cycle. The difference between Newtonian and non-Newtonian blood models is also studied over the whole cardiac cycle using the recently generalised global non-Newtonian importance factor. In addition, the flow is studied by considering paths of massless particles introduced into the flow field.The study shows that, when studying the wall shear stress distribution for transient blood flow in arteries, the use of a Newtonian blood model is a reasonably good approximation. However, to study the flow within the artery in greater detail, a non-Newtonian model is more appropriate. (c) 2005 Elsevier Ltd. All rights reserved.