Prevalence of epilepsy in the People's Republic of China: A systematic review

Prevalence of epilepsy in the People's Republic of China: A systematic review
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DOI:
10.1016/j.eplepsyres.2013.02.002
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发表时间:
2013-07-01
期刊:
影响因子:
2.2
通讯作者:
Su, Li
Su, Li
中科院分区:
医学4区
文献类型:
--
作者:
Gu, Lian;Liang, Baoyun;Su, Li

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到目前为止,还没有关于中国癫痫患病率的全国性系统分析。本研究的目的是从已发表的研究中估计中国在内地的癫痫患病率,并从调查方法、性别、地点、年龄、癫痫发作类型和患病日期等方面分析癫痫的患病率。计算机检索PubMed、Embase、中国生物医学文献数据库(CBM)、中国国家知识基础设施(CNKI)、中国万方和重庆维普数据库,进行癫痫流行病学研究。纳入了38项研究,总样本量为7,695,961人,其中13,224人患有癫痫。癫痫的总患病率为2.89‰。男、女患病率分别为3.83‰和3.45‰。城市和农村的不同地点患病率分别为2.34‰和3.17‰。按年龄分组,0-9、10-19、20-29、30-39、40-49、50-59、60-69和<gt;=70的患病率分别为2.21‰、3.23‰、3.14‰、2.83‰、2.96‰、2.61‰、2.76‰和2.22‰。按发病日期分组分析,癫痫患病率为1.19‰~6.70‰。就发作类型而言,全面性发作、部分性发作和无法分类发作的总体患病率分别为3.12‰、0.57‰和0.23‰。总体而言,中国的癫痫患病率在内地各地区有所不同。在按男性、农村、10-19岁年龄组和全身性癫痫发作进行的亚组分析中,癫痫的患病率较高。然而,还需要从其他省份进行更多的流行病学研究,以估计内地中国癫痫的总体患病率。(C)2013爱思唯尔B.V.保留所有权利。
To date there has not been a nationwide systematic analysis of the prevalence of epilepsy in China. The aim of this study was to estimate the prevalence of epilepsy in mainland China from the published studies and analyze the prevalence of epilepsy by survey method, gender, location, age, seizure type and prevalence of date. We searched the PubMed, Embase, Chinese Biological Medical Literature (CBM), Chinese National Knowledge Infrastructure (CNKI), Chinese Wanfang and Chongqing VIP databases for epidemiological studies on the prevalence of epilepsy. Thirty-eight studies were included that comprised a total sample size of 7,695,961, among whom 13,224 had epilepsy. The overall prevalence of epilepsy was 2.89 parts per thousand. The prevalence of males and females were 3.83 parts per thousand and 3.45 parts per thousand, respectively. The location-specific prevalence in urban and rural areas was 2.34 parts per thousand and 3.17 parts per thousand, respectively. Prevalence by age groups, 0-9, 10-19, 20-29, 30-39, 40-49, 50-59, 60-69 and >= 70 were 2.21 parts per thousand, 3.23 parts per thousand, 3.14 parts per thousand, 2.83 parts per thousand, 2.96 parts per thousand, 2.61 parts per thousand, 2.76 parts per thousand and 2.22 parts per thousand, respectively. In the subgroup analysis by prevalence date, prevalence rate of epilepsy ranged from 1.19 parts per thousand to 6.70 parts per thousand. As for the seizure types, the overall prevalence of generalized seizures, partial seizures and unclassifiable seizures were 3.12 parts per thousand, 0.57 parts per thousand and 0.23 parts per thousand, respectively. Overall, the prevalence rate of epilepsy is different for each area in mainland China. A higher prevalence of epilepsy is found in the subgroup analysis by male, rural, age group of 10-19 and generalized seizures. However, more epidemiological studies are needed from other provinces to estimate the overall prevalence of epilepsy in mainland China. (C) 2013 Elsevier B.V. All rights reserved.