Association between the dietary approaches to hypertension diet and hypertension in youth with diabetes mellitus.
Association between the dietary approaches to hypertension diet and hypertension in youth with diabetes mellitus.
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DOI：
10.1161/hypertensionaha.108.116665
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发表时间：
2009-01
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影响因子：
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通讯作者：
Mayer-Davis EJ
中科院分区：
文献类型：
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作者：
Günther AL;Liese AD;Bell RA;Dabelea D;Lawrence JM;Rodriguez BL;Standiford DA;Mayer-Davis EJ
在患有糖尿病的年轻人中，血压升高是最常见的并存疾病之一。因此，探索有助于预防或控制这一人群高血压的饮食因素是至关重要的。我们从青年糖尿病研究中调查了坚持饮食方法以停止高血压(DASH)是否与患有糖尿病的青年糖尿病患者的高血压有关。2001至2005年间，2,830名10至22岁的青年(2,440名患有1,390名2型糖尿病患者)完成了一次学习访问。对于8个DASH食物组，当满足DASH建议时，每组都被分配了10分。较低的进食量按比例进行评分，并将8个人的得分相加。采用多元Logistic回归分析DASH总分与高血压之间的关系。青年1型高血压患病率为6.8%，2型糖尿病为28.2%。在1型青年中，对DASH的更高依从性与高血压呈负相关，与人口统计学、临床和行为特征无关(三位数2对1：或0.7，95%可信区间0.5~1.0；3对1：0.6，0.4~0.9；趋势=0.007)。对于2型糖尿病，DASH饮食与高血压无关(四元组2：0.8，0.5-1.4；三元组：0.9，0.5-1.5；趋势=0.6)。需要进行前瞻性观察研究或临床试验，以调查遵守DASH指南是否有助于预防青年1型糖尿病患者的高血压。对于2型糖尿病，更多的研究和更大的样本是必要的。
Among youth with diabetes mellitus, elevated blood pressure represents one of the most common co-morbidities. Hence, exploring dietary factors that may help prevent or control hypertension in this population is of paramount importance. We investigated whether adherence to the Dietary Approaches to Stop Hypertension (DASH) is associated with hypertension in youth with diabetes from the SEARCH for Diabetes in Youth Study. Between 2001 and 2005, 2,830 youth aged 10 to 22 years (2,440 with type 1,390 with type 2 diabetes) completed a study visit. For each of the 8 DASH food groups, a score of 10 was assigned when the DASH recommendation was met. Lower intakes were scored proportionately, and the 8 individual scores were summed. The association between the overall DASH score and hypertension was evaluated using multiple logistic regression. The crude prevalence of hypertension was 6.8% for youth with type 1 and 28.2 % for type 2 diabetes. In youth with type 1, a higher adherence to DASH was inversely related to hypertension, independent of demographic, clinical, and behavioral characteristics (tertile 2 vs. 1: OR 0.7, 95% CI 0.5–1.0; 3 vs. 1: 0.6, 0.4–0.9; ptrend=0.007). For type 2 diabetes, the DASH diet was not associated with hypertension (tertile 2 vs. 1: 0.8, 0.5–1.4; 3 vs. 1: 0.9, 0.5–1.5; ptrend=0.6). Prospective observational studies or clinical trials are needed to investigate whether adherence to the DASH guidelines may help prevent hypertension in youth with type 1 diabetes. In type 2 diabetes, more research with a larger sample is necessary.