VALIDATION OF A COMBINED COMORBIDITY INDEX
VALIDATION OF A COMBINED COMORBIDITY INDEX
复制标题
DOI：
10.1016/0895-4356(94)90129-5
复制
发表时间：
1994-11-01
影响因子：
7.2
通讯作者：
GOLD, J
中科院分区：
文献类型：
--
作者：
CHARLSON, M;SZATROWSKI, TP;GOLD, J
本文的基本目的是评估一个队列的患者的年龄合并症指数，这些患者最初被纳入一项前瞻性研究，以确定围手术期并发症的风险因素。226例患者入组本研究。参与者是在1982年至1985年期间接受择期手术并存活出院的高血压或糖尿病患者。218名患者存活至出院。这些患者术后至少随访5年。每种合并症等级的估计相对死亡风险为1.4，每10岁为1.4。当年龄和合并症被建模为合并年龄合并症评分时，每个合并年龄合并症单位的估计相对风险为1.45。因此，合并症评分增加1所估计的死亡相对风险被证明近似等于年龄增加10岁所估计的死亡相对风险。在一些纵向研究中，联合年龄-共病评分可能有助于从预后临床协变量中估计死亡的相对风险。
The basic objective of this paper is to evaluate an age-comorbidity index in a cohort of patients who were originally enrolled in a prospective study to identify risk factors for peri-operative complications. Two-hundred and twenty-six patients were enrolled in the study. The participants were patients with hypertension or diabetes who underwent elective surgery between 1982 and 1985 and who survived to discharge. Two-hundred and eighteen patients survived until discharge. These patients were followed for at least five years post-operatively. The estimated relative risk of death for each comorbidity rank was 1.4 and for each decade of age was 1.4. When age and comorbidity were modelled as a combined age-comorbidity score, the estimated relative risk for each combined age-comorbidity unit was 1.45. Thus, the estimated relative risk of death from an increase of one in the comorbidity score proved approximately equal to that from an additional decade of age. The combined age-comorbidity score may be useful in some longitudinal studies to estimate relative risk of death from prognostic clinical covariates.