The role of comorbidity in explaining the associations between anxiety disorders and smoking
The role of comorbidity in explaining the associations between anxiety disorders and smoking
复制标题
DOI：
10.1093/ntr/ntq006
复制
发表时间：
2010-04-01
影响因子：
4.7
通讯作者：
Sachs-Ericsson, Natalie
中科院分区：
文献类型：
--
作者：
Cougle, Jesse R.;Zvolensky, Michael J.;Sachs-Ericsson, Natalie
研究普遍发现吸烟和焦虑症之间有很强的联系。本研究旨在探讨科摩罗在解释这些关系中的作用，参与者来自科摩罗全国重复调查（N = 5，692）。使用世界卫生组织复合国际诊断访谈的世界精神卫生调查倡议版本评估轴I障碍。此外，吸烟和精神健康治疗史进行了评估。多变量分析人口统计学变量和精神和物质使用共病协变发现，创伤后应激障碍是唯一相关的每一个感兴趣的吸烟结果，包括12个月和终身每天和大量吸烟，尼古丁依赖和戒烟失败。广泛性焦虑症和社交焦虑症与较少的吸烟相关结果相关，与预测相反，惊恐障碍仅与12个月的每日吸烟独立相关。然而，惊恐发作史与12个月的每日重度吸烟、尼古丁依赖和终生戒烟失败唯一相关。此外，分析表明，焦虑症的数量越多，每种吸烟结果的患病率越高，即使是一种焦虑症的存在也与吸烟患病率升高有关。研究结果表明，合并症可能只能解释与吸烟困难的一些焦虑症的协会。
Research has generally found strong associations between smoking and anxiety disorders. The present study sought to examine the role of comorbidity in explaining these relationships.Participants from the National Comorbidity Survey-Replication (N = 5,692) were included in the present study. Axis I disorders were assessed using the World Mental Health Survey Initiative version of the World Health Organization Composite International Diagnostic Interview. In addition, smoking and mental health treatment history were assessed.Multivariate analyses covarying for demographic variables and psychiatric and substance use comorbidity found that posttraumatic stress disorder was uniquely associated with every smoking outcome of interest, including 12-month and lifetime daily and heavy smoking, nicotine dependence, and cessation failure. Generalized anxiety disorder and social anxiety disorder were associated with fewer smoking-related outcomes, and contrary to predictions, panic disorder was only independently associated with 12-month daily smoking. Panic attack history, however, was uniquely associated with 12-month daily and heavy smoking, nicotine dependence, and lifetime cessation failure. In addition, analyses indicated that greater number of anxiety disorders was associated with greater prevalence of each smoking outcome, and the presence of even one anxiety disorder was associated with elevated smoking prevalence.Several specific anxiety disorders were found to be uniquely associated with smoking behavior. Findings suggest that comorbidity may only explain the associations with smoking difficulties for some anxiety disorders.