Prognostic value of parapharyngeal extension in nasopharyngeal carcinoma treated with intensity modulated radiotherapy

Prognostic value of parapharyngeal extension in nasopharyngeal carcinoma treated with intensity modulated radiotherapy
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咽旁延长术对鼻咽癌调强放疗的预后价值

DOI:
10.1016/j.radonc.2013.10.007
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发表时间:
2014-03-01
影响因子:
5.7
通讯作者:
Ma, Jun
Ma, Jun
中科院分区:
医学1区
文献类型:
--
作者:
Tang, Ling-Long;Sun, Ying;Ma, Jun

文献摘要

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背景和目的:随着诊断和治疗技术的发展,鼻咽癌的治疗发生了革命性的变化。本研究的目的是重新评估鼻咽癌咽旁延伸的预后价值在IMRT时代。材料和方法:我们回顾性分析了749例活检证实的非转移性鼻咽癌患者的数据。所有患者均行MRI检查,并接受调强放疗(IMRT)作为初步治疗。无病生存率差异有统计学意义(DFS; 70.3% vs. 89.1%,P
Background and purpose: The development of improved diagnostic and therapeutic techniques has revolutionized the management of nasopharyngeal carcinoma (NPC). The purpose of this study is to revaluate the prognostic value of parapharyngeal extension in NPC in the IMRT era.Material and methods: We retrospectively reviewed data from 749 biopsy-proven non-metastatic NPC patients. All patients were examined with magnetic resonance imaging (MRI) and received intensity-modulated radiotherapy (IMRT) as the Primary treatment.Results: The incidence of parapharyngeal extension was 72.1%. A significant difference was observed in the disease-free survival (DFS; 70.3% vs. 89.1%, P