Multiscale Design and Multiobjective Optimization of Orthopedic Hip Implants with Functionally Graded Cellular Material
Multiscale Design and Multiobjective Optimization of Orthopedic Hip Implants with Functionally Graded Cellular Material
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DOI：
10.1115/1.4006115
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发表时间：
2012-03-01
影响因子：
1.7
通讯作者：
Pasini, Damiano
中科院分区：
文献类型：
--
作者：
Khanoki, Sajad Arabnejad;Pasini, Damiano
全髋关节置换术的翻修手术通常是由于植入物的结构相容性缺陷引起的。其中两个主要罪魁祸首是骨-种植体界面不稳定和骨吸收。为了解决这些问题，在本文中，我们提出了一种新型植入物，与目前由全固体或泡沫材料制成的髋关节置换植入物相比，该植入物由材料性能不均匀分布的晶格微结构组成。引入基于多尺度力学和设计优化的方法来合成分级细胞植入物，该植入物可以最大程度地减少同时发生的骨吸收和植入物界面失效。该程序应用于具有优化的相对密度梯度的二维左植入股骨的设计。为了评估分级细胞微观结构的可制造性，通过使用快速原型制作进行了概念验证。分析结果用于将优化的细胞植入物与全致密钛植入物和相对密度为 50% 的均质泡沫植入物进行比较。细胞植入物的骨吸收和界面应力最大值分别比钛植入物小70%和50%以上，比泡沫植入物小53%和65%。 [DOI：10.1115/1.4006115]
Revision surgeries of total hip arthroplasty are often caused by a deficient structural compatibility of the implant. Two main culprits, among others, are bone-implant interface instability and bone resorption. To address these issues, in this paper we propose a novel type of implant, which, in contrast to current hip replacement implants made of either a fully solid or a foam material, consists of a lattice microstructure with nonhomogeneous distribution of material properties. A methodology based on multiscale mechanics and design optimization is introduced to synthesize a graded cellular implant that can minimize concurrently bone resorption and implant interface failure. The procedure is applied to the design of a 2D left implanted femur with optimized gradients of relative density. To assess the manufacturability of the graded cellular microstructure, a proof-of-concept is fabricated by using rapid prototyping. The results from the analysis are used to compare the optimized cellular implant with a fully dense titanium implant and a homogeneous foam implant with a relative density of 50%. The bone resorption and the maximum value of interface stress of the cellular implant are found to be over 70% and 50% less than the titanium implant while being 53% and 65% less than the foam implant. [DOI: 10.1115/1.4006115]