Is Social Jetlag Associated with an Adverse Endocrine, Behavioral, and Cardiovascular Risk Profile?
Is Social Jetlag Associated with an Adverse Endocrine, Behavioral, and Cardiovascular Risk Profile?
复制标题
DOI：
10.1177/0748730414550199
复制
发表时间：
2014-10-01
影响因子：
3.5
通讯作者：
Dekker, Jacqueline M.
中科院分区：
文献类型：
--
作者：
Rutters, Femke;Lemmens, Sofie G.;Dekker, Jacqueline M.
社会时差代表了生理时钟和社会时钟之间的差异，这是用工作日和休息日之间睡眠中间时间的差异来衡量的。此前的研究表明，社交时差与身体质量指数（BMI）、糖化血红蛋白水平、心率、抑郁症状、吸烟、精神困扰和饮酒有关。我们当前研究的目的是调查145名表面健康的参与者（67名男性和78名女性，年龄18-55岁，BMI 18-35 kg/m(2)），社交时差的患病率及其与体内测量的不良内分泌、行为和心血管风险概况的关系。与有1小时社交时差的参与者相比，有2小时社交时差的参与者有更高的5小时皮质醇水平，一周内睡眠更少，更经常不运动，静息心率更高。因此，我们得出结论，在表面健康的参与者中，社交时差与不利的内分泌、行为和心血管风险有关。这些不利的情况使健康的参与者在不久的将来有可能患上代谢性疾病和精神障碍，包括糖尿病和抑郁症。
Social jetlag represents the discrepancy between circadian and social clocks, which is measured as the difference in hours in midpoint of sleep between work days and free days. Previous studies have shown social jetlag to be associated with body mass index (BMI), glycated hemoglobin levels, heart rate, depressive symptoms, smoking, mental distress and alcohol use. The objective of our current study was to investigate, in a group of 145 apparently healthy participants (67 men and 78 women, aged 18-55 years, BMI 18-35 kg/m(2)), the prevalence of social jetlag and its association with adverse endocrine, behavioral and cardiovascular risk profiles as measured in vivo. participants with 2 h social jetlag had higher 5-h cortisol levels, slept less during the week, were more often physically inactive and had an increased resting heart rate, compared with participants who had 1 h social jetlag. We therefore concluded that social jetlag is associated with an adverse endocrine, behavioral and cardiovascular risk profile in apparently healthy participants. These adverse profiles put healthy participants at risk for development of metabolic diseases and mental disorders, including diabetes and depression, in the near future.