Stereoselective Synthesis of Unsymmetrical Conjugated Dienes and Trienes Utilizing Silacyclobutenes.
Stereoselective Synthesis of Unsymmetrical Conjugated Dienes and Trienes Utilizing Silacyclobutenes.
复制标题
DOI：
10.1002/chin.200736054
复制
发表时间：
2007-05
期刊：
影响因子：
--
通讯作者：
C. K. Jin;Toshiaki Yamada;S. Sano;M. Shiro;Y. Nagao
中科院分区：
文献类型：
--
作者：
C. K. Jin;Toshiaki Yamada;S. Sano;M. Shiro;Y. Nagao
不同类型的炔基取代的二芳基二芳基硅烷用茂锆-乙烯络合物CP2-Zr(CH2-CH2)处理，然后用3-N-HCl酸化，以较好的产率得到相应的区域和立体选择性的硅环丁烯。硅环丁烯用四丁基氟化铵脱硅，以较高的产率得到立体选择性的不对称共轭(1E，3E)-二烯和-三烯(R1或R2=1-环己烯基)。
Treatment of the different kinds of alkynyl-substituted dialkynyldiarylsilanes with zirconocene–ethylene complex Cp 2 Zr(CH 2 CH 2 ) followed by acidification with 3 N HCl gave regio- and stereoselectively the corresponding silacyclobutenes in good yields. Desilylation of the silacyclobutenes with tetrabutylammonium fluoride afforded stereoselectively unsymmetrical conjugated (1 E ,3 E )-dienes and -trienes (R 1 or R 2 = 1-cyclohexenyl) in excellent yields.