Validation of numerically simulated ventricular flow patterns during left ventricular assist device support.
Validation of numerically simulated ventricular flow patterns during left ventricular assist device support.
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DOI：
10.1177/0391398820904056
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发表时间：
2021-01
期刊：
影响因子：
--
通讯作者：
Aigner P
中科院分区：
文献类型：
--
作者：
Ghodrati M;Khienwad T;Maurer A;Moscato F;Zonta F;Schima H;Aigner P
多个小组已通过计算流体动力学研究了左心室辅助装置支持期间的心室内流动模式。基于此类模拟，开发了血栓形成风险分析的具体参数。然而，复杂流动配置的计算流体动力学模拟需要通过实验进行适当的验证。为了满足这一需求，通过粒子图像测速法分析了具有明确流入截面的心室模型，并通过瞬态计算流体动力学模拟进行了复制。为了涵盖层流、过渡流和湍流流态，应用了四种数值方法，包括层流、标准 k-omega、剪切应力传递和重正化群 k-epsilon，并与整个左心室 46 个不同平面的粒子图像测速结果进行比较。除重整化组 k-epsilon 外，所有方法的模拟血流模式均与使用粒子图像测速法测量的血流模式相当（整个左心室的绝对误差：层流：10.5，标准 k-omega：11.3，剪切应力传递：11.3，以及重整化组 k-epsilon：17.8 mm/s）。使用四种数值方法模拟心室内流场，并用实验粒子图像测速结果进行验证。在给定的设置和选定的边界条件下，层流、标准 K-omega 和剪切应力传输方法与实验粒子图像测速数据显示出可接受的相似性，层流模型显示出最佳的瞬态行为。
Intraventricular flow patterns during left ventricular assist device support have been investigated via computational fluid dynamics by several groups. Based on such simulations, specific parameters for thrombus formation risk analysis have been developed. However, computational fluid dynamic simulations of complex flow configurations require proper validation by experiments. To meet this need, a ventricular model with a well-defined inflow section was analyzed by particle image velocimetry and replicated by transient computational fluid dynamic simulations. To cover the laminar, transitional, and turbulent flow regime, four numerical methods including the laminar, standard k-omega, shear-stress transport, and renormalized group k-epsilon were applied and compared to the particle image velocimetry results in 46 different planes in the whole left ventricle. The simulated flow patterns for all methods, except renormalized group k-epsilon, were comparable to the flow patterns measured using particle image velocimetry (absolute error over whole left ventricle: laminar: 10.5, standard k-omega: 11.3, shear–stress transport: 11.3, and renormalized group k-epsilon: 17.8 mm/s). Intraventricular flow fields were simulated using four numerical methods and validated with experimental particle image velocimetry results. In the given setting and for the chosen boundary conditions, the laminar, standard K-omega, and shear–stress transport methods showed acceptable similarity to experimental particle image velocimetry data, with the laminar model showing the best transient behavior.
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