In-hospital cardiac arrest in patients with coronavirus 2019.
In-hospital cardiac arrest in patients with coronavirus 2019.
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DOI：
10.1016/j.resuscitation.2021.01.012
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发表时间：
2021-03
期刊：
影响因子：
6.5
通讯作者：
Coronavirus 2019 In-Hospital Cardiac Arrest (COVID IHCA) Study Group
中科院分区：
文献类型：
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作者：
Mitchell OJL;Yuriditsky E;Johnson NJ;Doran O;Buckler DG;Neefe S;Seethala RR;Motov S;Moskowitz A;Lee J;Griffin KM;Shashaty MGS;Horowitz JM;Abella BS;Coronavirus 2019 In-Hospital Cardiac Arrest (COVID IHCA) Study Group
截至2020年11月，冠状病毒病2019(新冠肺炎)已在全球造成超过120万人死亡。然而，院内心脏骤停后新冠肺炎活动期住院患者的临床转归知之甚少。我们的目标是确定新冠肺炎患者行IHCA治疗的结果，并确定与30天存活期相关的患者和医院水平的变量。我们在美国11个学术医疗中心进行了一项多中心的回顾性队列研究。纳入了在2020年3月1日至2020年5月31日期间接受心肺复苏和/或除颤治疗的严重急性呼吸综合征冠状病毒2型阳性的成人患者。主要结果是IHCA后30天的存活。在研究期间，新冠肺炎患者中有260个IHCA。中位年龄为69岁(四分位数范围为60-77)，其中71.5%为男性，49.6%为白人，16.9%为黑人，16.2%为西班牙裔。最常见的出现节律为无脉搏电活动(45.0%)和停搏(44.6%)。ROSC发生58例(22.3%)，31例(11.9%)存活至出院，32例(12.3%)存活至30天。在研究期间，与其余医院相比，IHCA数量最多的两家医院的ROSC率和30天存活率都要低得多(分别为10.8%比64.3%和5.9%比35.7%，p <； 0.001)。ROSC和30天存活率分别为22.3%和12.3%。中心水平的结果有很大的差异，这可能解释了先前研究中存活率较低的原因。
Coronavirus Disease 2019 (COVID-19) has caused over 1 200 000 deaths worldwide as of November 2020. However, little is known about the clinical outcomes among hospitalized patients with active COVID-19 after in-hospital cardiac arrest (IHCA). We aimed to characterize outcomes from IHCA in patients with COVID-19 and to identify patient- and hospital-level variables associated with 30-day survival. We conducted a multicentre retrospective cohort study across 11 academic medical centres in the U.S. Adult patients who received cardiopulmonary resuscitation and/or defibrillation for IHCA between March 1, 2020 and May 31, 2020 who had a documented positive test for Severe Acute Respiratory Syndrome Coronavirus 2 were included. The primary outcome was 30-day survival after IHCA. There were 260 IHCAs among COVID-19 patients during the study period. The median age was 69 years (interquartile range 60–77), 71.5% were male, 49.6% were White, 16.9% were Black, and 16.2% were Hispanic. The most common presenting rhythms were pulseless electrical activity (45.0%) and asystole (44.6%). ROSC occurred in 58 patients (22.3%), 31 (11.9%) survived to hospital discharge, and 32 (12.3%) survived to 30 days. Rates of ROSC and 30-day survival in the two hospitals with the highest volume of IHCA over the study period compared to the remaining hospitals were considerably lower (10.8% vs. 64.3% and 5.9% vs. 35.7% respectively, p < 0.001 for both). We found rates of ROSC and 30-day survival of 22.3% and 12.3% respectively. There were large variations in centre-level outcomes, which may explain the poor survival in prior studies.
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影响因子：
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作者：
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通讯作者：
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DOI：
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DOI：
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发表时间：
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期刊：
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影响因子：
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作者：
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