STUDIES IN HUMAN LACTATION - MILK-COMPOSITION AND DAILY SECRETION RATES OF MACRONUTRIENTS IN THE 1ST YEAR OF LACTATION
STUDIES IN HUMAN LACTATION - MILK-COMPOSITION AND DAILY SECRETION RATES OF MACRONUTRIENTS IN THE 1ST YEAR OF LACTATION
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DOI：
10.1093/ajcn/54.1.69
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发表时间：
1991-07-01
影响因子：
7.1
通讯作者：
NEVILLE, MC
中科院分区：
文献类型：
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作者：
ALLEN, JC;KELLER, RP;NEVILLE, MC
本文对13例经产妇女从妊娠到纯母乳喂养6个月的乳汁成分和分泌物随时间的变化进行了研究。 从第6天至断奶开始，纵向分析脂质、乳糖、蛋白质、钠、氯化物、钾、总钙、离子钙、镁、葡萄糖、柠檬酸盐、无机磷酸盐、肌酐和尿素的浓度和分泌速率以及pH值。 产前分泌物的组成与乳腺细胞间连接复合体的通透性有关。 在1至6个月之间观察到乳糖、葡萄糖、pH值和离子钙显著增加，蛋白质、钠、钾、氯和钙浓度显著降低。 个体之间的显着差异，持续通过哺乳期，观察到的钠，钾，氯化物和无机磷酸盐的浓度。 转移到婴儿体内的乳糖、离子钙和镁的量也是每对母婴的特征。 我们的数据表明，泌乳性能是在产后第一个月决定的。
Time-dependent changes in milk composition and secretion from pregnancy through greater-than-or-equal-to 6 mo of exclusive breast-feeding were studied in 13 multiparous women. Concentrations and secretion rates of lipid, lactose, protein, sodium, chloride, potassium, total calcium, ionized calcium, magnesium, glucose, citrate, inorganic phosphate, creatinine, and urea and pH were analyzed longitudinally from day 6 until weaning commenced. The composition of the antepartum secretion was related to the permeability of the junctional complexes between mammary cells. Significant increases in lactose, glucose, pH, and ionized calcium and significant decreases in protein, sodium, potassium, chloride, and calcium concentrations were observed between 1 and 6 mo. Significant differences among individuals, which persisted through lactation, were observed for the concentrations of sodium, potassium, chloride, and inorganic phosphate. The amount of lactose, ionized calcium, and magnesium transferred to the infant was also characteristic of each mother-infant pair. Our data imply that lactation performance is determined in the first month postpartum.