ELEVATION OF FACTOR-VIII IN ACUTE LIVER NECROSIS - INFLUENCE OF PLASMAPHERESIS
ELEVATION OF FACTOR-VIII IN ACUTE LIVER NECROSIS - INFLUENCE OF PLASMAPHERESIS
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DOI：
10.1159/000197336
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发表时间：
1973-01-01
期刊：
影响因子：
3.2
通讯作者：
BARBIER, F
中科院分区：
文献类型：
--
作者：
BAELE, G;VERMEIRE, P;BARBIER, F
报告3例急性病毒性肝坏死患者血浆置换术中凝血试验结果。血浆置换开始前，所有病例均出现fviii水平升高。血浆置换过程中，2例患者fviii活性降低。第三例患者在血浆置换数天内fviii水平持续高，可能存在弥散性血管内凝血。本文讨论了急性病毒性肝坏死中fviii升高的机制以及血浆置换对fviii水平的影响。
The results of clotting tests during plasmapheresis in 3 cases of acute viral liver necrosis are reported. Elevated F VIII levels were found in all cases before the start of plasmapheresis. During plasmapheresis, a decrease of F VIII activity was found in 2 cases. In the third patient with persistently high F VIII levels during several days of plasmapheresis, disseminated intravascular coagulation may have been present. The mechanisms of the elevation of F VIII in acute viral liver necrosis and the influence of plasmapheresis on F VIII levels are discussed.