Coming or going? Un-BLOC-ing delivery and recycling pathways during melanosome maturation.
Coming or going? Un-BLOC-ing delivery and recycling pathways during melanosome maturation.
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DOI：
10.1083/jcb.201607023
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发表时间：
2016-08-01
期刊：
影响因子：
--
通讯作者：
Cutler DF
中科院分区：
文献类型：
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作者：
Futter CE;Cutler DF
黑素体的生物发生需要从内体到未成熟黑素体的连续波货物输送，以及运输机制的回收。丹尼斯等人。 (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201605090) 报道了 BLOC-1 和 BLOC-3 复合物在黑素体生物遗传成分的递送和回收中的不同作用，为黑素体成熟提供方向性。
Melanosome biogenesis requires successive waves of cargo delivery from endosomes to immature melanosomes, coupled with recycling of the trafficking machinery. Dennis et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201605090) report differential roles for BLOC-1 and BLOC-3 complexes in delivery and recycling of melanosomal biogenetic components, supplying directionality to melanosome maturation.