Transfer function through regional cerebral cortex evaluated by a photoelectric method.
Transfer function through regional cerebral cortex evaluated by a photoelectric method.
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通过光电方法评估通过区域大脑皮层的传递功能。
DOI：
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发表时间：
1983
影响因子：
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通讯作者：
B. Mihara
中科院分区：
文献类型：
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作者：
M. Tomita;F. Gotoh;T. Amano;N. Tanahashi;M. Kobari;T. Shinohara;B. Mihara
报道了一种通过局部大脑皮层获得传递函数的新技术。颈动脉注射1/40稀释的炭黑溶液0.2ml后，以光电密度计为测量头，记录组织炭黑(CB)稀释曲线。对血管系统的线性和稳定性、曲线的重复性和再循环进行了测试。组织CB稀释曲线是一个累积分布函数，首先求出两条曲线，即入口曲线和出口曲线。通过使用伽马密度函数进行外推，修正了由“重叠”引起的误差。然后通过入口和出口曲线的数值反卷积来计算通过皮质的传递函数。通过与从软脑膜动脉和上矢状窦同时记录的实际CB稀释曲线的比较，验证了计算传递函数的有效性。进一步对传递函数进行矩分析，以确定大脑皮质的实质内循环参数。文中给出了一些实例，说明了该技术的适用性。
A new technique is reported for obtaining the transfer function through the regional cerebral cortex. Tissue carbon-black (CB) dilution curves were recorded with a photoelectric apparatus used as a densitometer head in cat cortex in situ following intracarotid injection of 0.2 ml of 1/40 diluted CB solution. The linearity and stationarity of the vascular system, reproducibility of the curve, and recirculation were tested. The tissue CB dilution curve, a cumulative distribution function, was first differentiated yielding two curves comprising the inlet and outlet curves. The error due to "overlapping" was corrected for by extrapolation using the gamma-density function. The transfer function through the cortex was then calculated by numerical deconvolution of the inlet and outlet curves. The validity of the calculated transfer function was verified by comparison with that obtained from actual CB dilution curves recorded simultaneously from the pial artery and superior sagittal sinus. The transfer function was further subjected to moment analysis for determining the intraparenchymal circulatory parameters of the cerebral cortex. Some examples demonstrating the applicability of technique are given.