Effect of zinc on liver cirrhosis with hyperammonemia: A preliminary randomized, placebo-controlled double-blind trial
Effect of zinc on liver cirrhosis with hyperammonemia: A preliminary randomized, placebo-controlled double-blind trial
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DOI：
10.1016/j.nut.2014.04.018
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发表时间：
2014-11-01
期刊：
影响因子：
4.4
通讯作者：
Suzuki, Kazuyuki
中科院分区：
文献类型：
--
作者：
Katayama, Kazuhiro;Saito, Masanori;Suzuki, Kazuyuki
目的：据我们所知，尚无随机研究表明锌替代疗法对肝硬化高氨血症是否有效。因此，我们进行了一项双盲、安慰剂对照试验，以检验锌替代疗法的有效性和安全性。 方法：患有肝硬化和高氨血症（等于或高于机构参考值）和低锌血症（
Objective: To our knowledge, no randomized study has shown whether zinc replacement therapy is effective for hyperammonemia in liver cirrhosis; therefore, we performed a double-blind, placebo-controlled trial to examine efficacy and safety of the zinc replacement therapy.Methods: Patients with liver cirrhosis and hyperammonemia (at or above the institutional reference value) and hypozincemia (