Antidepressant Prescribing in Primary Care to Older Adults Without Major Depression
Antidepressant Prescribing in Primary Care to Older Adults Without Major Depression
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DOI：
10.1176/appi.ps.201600197
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发表时间：
2017-05-01
影响因子：
3.8
通讯作者：
Kales, Helen C.
中科院分区：
文献类型：
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作者：
Maust, Donovan T.;Sirey, Jo Anne;Kales, Helen C.
目的：该研究比较了两组老年人的痛苦水平，他们的初级保健医生新开了一种抗抑郁药，患有重度抑郁症（MDD）的人和没有MDD的人。该分析使用了方便的参与者样本（N=231）在一项旨在改善抗抑郁药依从性和抑郁症结局的随机对照试验中，老年人（>= 55）。在确定了患有和不患有MDD的参与者的比例（使用DSM-IV的结构化临床访谈）后，作者比较了人口统计学，临床和心理社会特征，包括12项简表健康调查身体和精神成分汇总评分（PCS和MCS）。Logistic回归被用来测试这些特征与抗抑郁药的使用在没有MDD。结果：大多数（57%）的参与者没有MDD。该组年龄较大（69.4 vs 64.7，p
Objective: The study compared distress levels among two groups of older adults who had been newly prescribed an antidepressant by their primary care physician, those with major depressive disorder (MDD) and those without MDD.Methods: This analysis used a convenience sample of participants (N=231) who had been newly prescribed an antidepressant in a randomized controlled trial of a program to improve antidepressant adherence and depression outcomes among older adults (>= 55). After determining the proportion of participants with and without MDD (using the Structured Clinical Interview for DSM-IV), the authors compared groups on demographic, clinical, and psychosocial characteristics, including the 12-Item Short-Form Health Survey physical and mental component summary scores (PCS and MCS). Logistic regression was used to test the association of these characteristics with antidepressant use in the absence of MDD.Results: Most (57%) participants did not have MDD. This group was older (69.4 versus 64.7, p