T-COMPLEX HEMISPHERIC ASYMMETRIES - EFFECTS OF STIMULUS-INTENSITY
T-COMPLEX HEMISPHERIC ASYMMETRIES - EFFECTS OF STIMULUS-INTENSITY
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DOI：
10.1016/0378-5955(88)90002-0
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发表时间：
1988-08-01
期刊：
影响因子：
2.8
通讯作者：
WOLPAW, JR
中科院分区：
文献类型：
--
作者：
CACACE, AT;DOWMAN, R;WOLPAW, JR
人类听觉诱发电位（AEP）的T复合物成分被认为是在颞叶后外侧表面的听觉皮层产生的。在颞部头皮上记录，包括80-90 ms的阳性峰Ta和120-140 ms的阴性峰Tb。作为开发T复合体在评估听觉皮质功能中的临床用途的一部分，我们研究了正常成人单耳刺激强度（20-80 dB SL）变化对T复合体潜伏期、振幅和半球差异的影响。Ta和Tb峰潜伏期随刺激强度的增加而降低。这些潜伏期变化不依赖于耳朵或半球。对侧刺激比同侧刺激右半球Ta潜伏期短；而左半球Ta潜伏期不依赖于受刺激的耳朵。结核潜伏期在左半球和对侧半球较短。Ta-b振幅随刺激强度的增大而增大。这种振幅变化不依赖于耳朵或半球。Ta-b振幅在右半球和对侧半球更大。刺激强度对大脑半球不对称无显著影响。
The T complex component of the human auditory evoked potential (AEP) is thought to be produced in auditory cortex, on the posterior lateral surface of the temporal lobe. Recorded over temporal scalp, it consists of an 80-90 ms positive peak, Ta, and a 120-140 negative peak, Tb. As part of an effort to develop the clinical usefulness of the T complex in assessing auditory cortical function, we studied the effects of change in monaural stimulus intensity (20-80 dB SL) on T complex latency, amplitude, and hemispheric differences in normal adults. Ta and Tb peak latencies decreased as stimulus intensity increased. These latency changes were not dependent on ear or hemisphere. Right hemisphere Ta latency was shorter with contralateral than with ipsilateral stimulation; while left hemisphere Ta latency was not dependent on the ear stimulated. Tb latency was shorter over the left hemisphere, and over the contralateral hemisphere. Ta-b amplitude increased as stimulus intensity increased. This amplitude change was not dependent on ear or hemisphere. Ta-b amplitudes were larger over the right hemisphere and over the contralateral hemisphere. Hemispheric asymmetries were not significantly affected by stimulus intensity.