Diversity, Stability, Recursivity, and Rule Generation in Biological System: Intra–Inter Dynamics Approach
Diversity, Stability, Recursivity, and Rule Generation in Biological System: Intra–Inter Dynamics Approach
复制标题
生物系统中的多样性、稳定性、递归性和规则生成：内-间动力学方法
DOI：
10.1142/s0217979298000223
复制
发表时间：
1998
影响因子：
1.7
通讯作者：
K. Kaneko
中科院分区：
文献类型：
--
作者：
K. Kaneko
讨论了构建生活场景的基本问题。为了从动力系统理论的角度研究这一问题，提出了一种内-间动力学的方案。它包括一个单元的内部动态，单元之间的相互作用，以及改变动态本身的动态，例如根据其内部状态复制（和死亡）单元。将此动力学应用于细胞分化，提出了细胞分化分化的多样性理论。根据它，轨道不稳定性首先导致多样化的细胞行为。在下一个阶段，形成了几种细胞类型，首先由振荡的集群触发，然后作为吸引状态的内部动态稳定的细胞间的相互作用。在第三阶段，通过细胞分裂将分化确定为递归状态。在最后一个阶段，等级分化继续进行，出现了分化为亚群的随机规则，其中分化概率的调节提供了细胞社会的多样性和稳定性。相关的理论细胞生物学进行了讨论。
Basic problems for the construction of a scenario for the life are discussed. To study the problems in terms of dynamical systems theory, a scheme of intra–inter dynamics is presented. It consists of internal dynamics of a unit, interaction among the units, and the dynamics to change the dynamics itself, for example by replication (and death) of units according to their internal states. Applying the dynamics to cell differentiation, isologous diversification theory is proposed. According to it, orbital instability leads to diversified cell behaviors first. At the next stage, several cell types are formed, first triggered by clustering of oscillations, and then as attracting states of internal dynamics stabilized by the cell-to-cell interaction. At the third stage, the differentiation is determined as a recursive state by cell division. At the last stage, hierarchical differentiation proceeds, with the emergence of stochastic rule for the differentiation to subgroups, where regulation of the probability for the differentiation provides the diversity and stability of cell society. Relevance of the theory to cell biology is discussed.
影响因子：
4.2
作者：
通讯作者：
--
DOI：
10.1016/s0167-2789(96)00282-5
发表时间：
1996-06
期刊：
Physica D: Nonlinear Phenomena
影响因子：
--
作者：
K. Kaneko
通讯作者：
K. Kaneko