APPLICATION OF POLYAMIDE RESINS TO POLYPEPTIDE-SYNTHESIS - IMPROVED SYNTHESIS OF BETA-ENDORPHIN USING "FLUORENYLMETHOXYCARBONYLAMINO-ACIDS
APPLICATION OF POLYAMIDE RESINS TO POLYPEPTIDE-SYNTHESIS - IMPROVED SYNTHESIS OF BETA-ENDORPHIN USING "FLUORENYLMETHOXYCARBONYLAMINO-ACIDS
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DOI：
10.1039/c39780000539
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发表时间：
1978-01-01
影响因子：
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通讯作者：
SHEPPARD, RC
中科院分区：
文献类型：
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作者：
ATHERTON, E;FOX, H;SHEPPARD, RC
使用碱不稳定的芴基甲氧羰基氨基酸能够固相合成人β-具有阿片样活性的内啡肽的制备在比以前温和得多的反应条件下进行，产物纯度和产率提高。
Use of base-labile fluorenylmethoxycarbonylamino acids enables solid phase peptide synthesis of human .beta.-endorphin with an opiate-like activity to be carried out under much milder reaction conditions than formerly with improvement in product purity and yield.