IL-17 cytokines in immunity and inflammation.

IL-17 cytokines in immunity and inflammation.
复制标题

DOI:
10.1038/emi.2013.58
复制
发表时间:
2013-09
影响因子:
13.2
通讯作者:
Dong, Chen
Dong, Chen
中科院分区:
医学2区
文献类型:
--
作者:
Jin, Wei;Dong, Chen

文献摘要

参考文献

被引文献

相似文献

白细胞介素17(IL-17)及其近亲IL-17 F近年来在免疫学领域引起了广泛关注。IL-17和IL-17 F由不同类型的T细胞、T辅助17细胞和某些其它淋巴细胞表达。这些细胞因子在宿主防御和炎性疾病中起关键的调节作用。本文综述了近年来IL-17生物学的研究进展以及IL-17表达调控机制和信号转导机制的研究进展。这些知识将有助于开发新的免疫调节剂,增强对各种感染的免疫力,减少感染患者的炎症损伤。
Interleukin 17 (IL-17) and its closest relative, IL-17F, have recently drawn much attention in the field of immunology. IL-17 and IL-17F are expressed by a distinct type of T cells, T helper 17 cells and certain other lymphocytes. These cytokines play key regulatory roles in host defense and inflammatory diseases. In this review, we summarize the recent findings in IL-17 biology and the progress towards understanding the regulatory mechanisms of IL-17 expression and signaling mechanisms. This knowledge will benefit the development of novel immune modulators that enhance immunity to various infections and reduce inflammatory damage in infected patients.
DOI: 10.1016/j.cellsig.2010.11.022
发表时间: 2011-07
影响因子: 4.8
作者:
Chang SH;Dong C
通讯作者: Dong C
DOI: 10.1016/s0014-5793(02)03688-8
发表时间: 2002-12-04
期刊: FEBS LETTERS
影响因子: 3.5
作者:
Kanamori, M;Kai, C;Suzuki, H
通讯作者: Suzuki, H
DOI: 10.4049/jimmunol.179.6.4135
发表时间: 2007-09-15
影响因子: 4.4
作者:
Hartupee, Justin;Liu, Caini;Hamilton, Thomas
通讯作者: Hamilton, Thomas
DOI: 10.1016/j.jaci.2004.03.047
发表时间: 2004-08-01
影响因子: 14.2
作者:
Kawaguchi, M;Kokubu, F;Huang, SK
通讯作者: Huang, SK
DOI: 10.1038/ni1254
发表时间: 2005-11-01
期刊: NATURE IMMUNOLOGY
影响因子: 30.5
作者:
Harrington, LE;Hatton, RD;Weaver, CT
通讯作者: Weaver, CT