Dynamic construction of a coherent attentional state in a prefrontal cell population.
Dynamic construction of a coherent attentional state in a prefrontal cell population.
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DOI：
10.1016/j.neuron.2013.07.041
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发表时间：
2013-10-02
期刊：
影响因子：
16.2
通讯作者：
Duncan J
中科院分区：
文献类型：
--
作者：
Kadohisa M;Petrov P;Stokes M;Sigala N;Buckley M;Gaffan D;Kusunoki M;Duncan J
前额叶皮层被认为具有高度适应性的信息编码，神经元动态地分配用于处理任务相关信息。为了跟踪这种动态分配在猴子前额叶皮层，我们使用时间分辨的措施，在一个简单的情况下，目标（行为关键）和非目标对象之间的竞争，在相反的视觉半野的神经群体活动。在处理过程的早期，对竞争性输入的反应是平行的，每个半球的神经元都被对侧刺激所控制。后来，非目标失去了对神经活动的控制，出现了行为关键目标的全局控制。过渡的速度反映了不同的显示元素的竞争力的权重，发生最迅速的相对行为的意义是建立了良好的训练历史。与自适应编码一致，结果表明，作为注意焦点的前额叶处理资源的广泛重新分配。前额叶神经元表现出有限注意资源的典型特性加工资源的划分损害神经元辨别的准确性随着加工的展开，神经元被重新分配给最重要的刺激，重新分配的速度和程度取决于相对注意权重，前额叶皮层像一个灵活的加工资源，可以对多种信息做出反应。Kadohisa等人展示了猴子前额叶皮层的神经元如何动态地重新分配，以在处理视觉显示时构建连贯的注意力焦点。
Prefrontal cortex has been proposed to show highly adaptive information coding, with neurons dynamically allocated to processing task-relevant information. To track this dynamic allocation in monkey prefrontal cortex, we used time-resolved measures of neural population activity in a simple case of competition between target (behaviorally critical) and nontarget objects in opposite visual hemifields. Early in processing, there were parallel responses to competing inputs, with neurons in each hemisphere dominated by the contralateral stimulus. Later, the nontarget lost control of neural activity, with emerging global control by the behaviorally critical target. The speed of transition reflected the competitive weights of different display elements, occurring most rapidly when relative behavioral significance was well established by training history. In line with adaptive coding, the results show widespread reallocation of prefrontal processing resources as an attentional focus is established. Prefrontal neurons show classic properties of a limited attentional resource Division of processing resources impairs accuracy of neural discriminations As processing unfolds, neurons are reallocated to the most important stimuli The speed and degree of reallocation depend on relative attentional weights Like a flexible processing resource, prefrontal cortex can respond to many kinds of information. Kadohisa et al. show how neurons in monkey prefrontal cortex are dynamically reallocated to construct a coherent attentional focus as a visual display is processed.
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影响因子：
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作者：
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通讯作者：
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DOI：
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