Concepts for differential diagnosis in breast MR imaging.

Concepts for differential diagnosis in breast MR imaging.
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DOI:
10.1016/j.mric.2006.07.002
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发表时间:
2006-08-01
影响因子:
1.6
通讯作者:
Kuhl, Christiane K
Kuhl, Christiane K
中科院分区:
医学4区
文献类型:
--
作者:
Kuhl, Christiane K

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与所有其他现代乳腺成像技术相比,乳腺MR成像对原发性和复发性浸润性乳腺癌的敏感性最高,这一点已得到广泛认同。然而,在很长一段时间里,这种方式一直被认为只提供有限的具体性。此外,据称导管内乳腺癌的低灵敏度阻碍了乳腺MR成像的更广泛使用。然而,最近的研究结果表明,乳腺MR成像的特异性和阳性预测值至少与乳腺X线摄影相当,导管原位癌(DCIS)的敏感性至少与乳腺X线摄影相当,如果不是更高的话。除了增加读者的经验,这一进展主要是由于这样一个事实,即在改善磁共振成像技术的同时,更精细的解释标准变得可用。这些标准可以大大改善恶性肿块和DCIS的诊断。本文概述了用于乳腺MR成像鉴别诊断的诊断标准的现状,以及乳腺MR成像可实现的诊断准确性。
There is broad agreement in that breast MR imaging, compared with all other contemporary breast imaging techniques, offers the highest sensitivity for primary and recurrent invasive breast cancer. For a long time, however, the modality suffered from the reputation of offering only a limited specificity. In addition, the allegedly low sensitivity for intraductal breast cancer hampered the more widespread use of breast MR imaging. More recent results, however, suggest that the specificity and positive predictive value of breast MR imaging are at least equivalent to those of mammography and that the sensitivity for ductal carcinoma in situ (DCIS) is at least comparable to mammography, if not higher. Apart from increasing reader experience, this progress is mainly attributable to the fact that in parallel with improved MR imaging technology, more refined interpretation criteria became available. These criteria allow a substantially improved diagnosis of malignant masses and of DCIS. This article provides an overview on the current status of the diagnosis criteria that are used for differential diagnosis in breast MR imaging and on the diagnostic accuracy that is achievable with breast MR imaging.