Carcinoma of the pancreas associated with anomalous junction of pancreaticobiliary tracts: report of two cases and review of the literature.

Carcinoma of the pancreas associated with anomalous junction of pancreaticobiliary tracts: report of two cases and review of the literature.
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DOI:
10.1007/s005340050019
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发表时间:
1998-01-01
期刊:
Journal of hepato-biliary-pancreatic surgery
影响因子:
--
通讯作者:
Tanaka, M
Tanaka, M
中科院分区:
其他
文献类型:
--
作者:
Kuga, H;Yamaguchi, K;Tanaka, M

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我们报告了两例伴有胰胆管异常连接的胰腺癌病例。一名71岁的日本女性患有阻塞性黄疸。超声检查显示胰头有低回声肿块,计算机断层扫描显示胰头有低密度结节。内镜逆行胰胆管造影显示双导管征和胰胆管的异常连接。该患者接受了胰十二指肠切除术。切除标本的组织病理学诊断为胰头腺癌。一名56岁的日本男子也出现了阻塞性黄疸。超声检查和计算机断层扫描显示巨大肿块几乎取代了整个胰腺,并累及肠系膜上动脉、脾动脉、脾静脉和门静脉。存在多发性肝转移和腹膜播散。内窥镜逆行胰胆管造影显示胰胆管的异常连接。患者因食管静脉曲张出血死亡。我们讨论胰胆管异常连接与胰腺癌之间的关系。
We report two cases of carcinoma of the pancreas with anomalous junction of the pancreaticobiliary tracts. A 71-year-old Japanese woman had obstructive jaundice. Ultrasonography showed a hypoechoic mass in the pancreatic head and computed tomography demonstrated a low-density nodule in the pancreatic head. Endoscopic retrograde cholangiopancreatography displayed a double duct sign and an anomalous junction of the pancreaticobiliary tracts. The patient underwent a pancreatoduodenectomy. The histopathologic diagnosis of the resected specimen was adenocarcinoma of the pancreatic head. A 56-year-old Japanese man also developed obstructive jaundice. Ultrasonography and computed tomography showed a huge mass almost replacing the whole pancreas and involving the superior mesenteric artery, splenic artery, splenic vein, and portal vein. Multiple hepatic metastases and peritoneal dissemination were present. Endoscopic retrograde cholangiopancreatography demonstrated an anomalous junction of the pancreaticobiliary tracts. The patient died of hemorrhage from esophageal varices. We discuss the relationship between the anomalous junction of the pancreaticobiliary tracts and pancreatic carcinoma.