Dermonecrotic loxoscelism in the Mediterranean region
Dermonecrotic loxoscelism in the Mediterranean region
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DOI：
10.3109/15569529909049325
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发表时间：
1999-01-01
期刊：
影响因子：
--
通讯作者：
Golik, A
中科院分区：
文献类型：
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作者：
Cohen, N;Sarafian, DA;Golik, A
在地中海地区，关于斜腹蛛咬伤的出版物很少。这种蜘蛛经常在以色列被发现，它的叮咬可能会导致严重的医疗问题。我们报告了11例患者谁持续这样的叮咬，并需要住院治疗，1988年至1997年在一个地区医院服务的人口30万。他们中的大多数是在夏天被咬伤的，10人在手臂或大腿的内侧。所有患者均表现出典型的loxosceles皮肤病变，全身表现明显，在六个。误诊7例。所有患者均接受抗生素治疗，8例患者加用皮质类固醇。10例患者在2-3周内完全康复，估计需要住院治疗的严重皮肤坏死性loxoscelism的发生率为0.37例/100，000人口/年。我们病例的临床病程似乎比美国报告的其他病例轻微。这可能是由于该地区的主要物种红腹蛛（Loxosceles rufescens）的叮咬。总之，这种临床实体是常见的，经常误诊。正确的诊断需要意识到并警惕loxosceles咬伤。
Publications on loxosceles spider bites in the Mediterranean region are scarce. This spider is frequently found in Israel and its bite may cause severe medical problem. We report on 11 patients who sustained such bites and required hospitalization between 1988 and 1997 in a regional hospital serving a population of 300,000. Most of them were bitten in the summer, 10 on the medial aspect of the arm or thigh. All patients exhibited the typical loxosceles skin lesion; systemic manifestations were evident in six. Seven patients were misdiagnosed. All were treated with antibiotics and eight with the addition of corticosteroids. Ten patients fully recovered within 2-3 weeks.The estimated incidence of severe dermonecrotic loxoscelism requiring hospitalization is 0.37 cases/100,000 population/year. It seems that the clinical course in our cases was somewhat milder than in other reported cases from the United States. This can possibly be attributed to the bite of Loxosceles rufescens, which is the prevailing species in this region. In conclusion, this clinical entity is common and frequently misdiagnosed. Appropriate diagnosis requires awareness of and alertness to loxosceles bite.