Reflectance confocal endomicroscope with optical axial scanning for in vivo imaging of the oral mucosa
Reflectance confocal endomicroscope with optical axial scanning for in vivo imaging of the oral mucosa
复制标题
DOI：
10.1364/boe.5.003781
复制
发表时间：
2014-11-01
影响因子：
3.4
通讯作者：
Maitland, Kristen C.
中科院分区：
文献类型：
--
作者：
Jabbour, Joey M.;Bentley, Julie L.;Maitland, Kristen C.
本文介绍了一种反射式共焦激光内窥镜的设计和评价，该显微镜使用刚性探针内的微型物镜透镜，并结合电调谐透镜进行轴向扫描。微型透镜的特点是单独以及在内窥镜在200 μ m的轴向扫描范围内使用可调透镜。共焦内窥镜探测人体口腔的能力是通过对体内口腔粘膜的成像来证明的。结果表明，反射共聚焦显微内镜有可能用于临床环境和指导生物组织的诊断评价。(C)2014年美国光学学会
This paper presents the design and evaluation of a reflectance confocal laser endomicroscope using a miniature objective lens within a rigid probe in conjunction with an electrically tunable lens for axial scanning. The miniature lens was characterized alone as well as in the endoscope across a 200 mu m axial scan range using the tunable lens. The ability of the confocal endoscope to probe the human oral cavity is demonstrated by imaging of the oral mucosa in vivo. The results indicate that reflectance confocal endomicroscopy has the potential to be used in a clinical setting and guide diagnostic evaluation of biological tissue. (C) 2014 Optical Society of America