Reasons for substance use in schizophrenia

Reasons for substance use in schizophrenia
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DOI:
10.1111/j.1600-0447.1997.tb09925.x
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发表时间:
1997-11-01
影响因子:
6.7
通讯作者:
Duchak, V
Duchak, V
中科院分区:
医学1区
文献类型:
--
作者:
Addington, J;Duchak, V

文献摘要

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精神分裂症患者对药物、酒精和其他物质的滥用和依赖日益得到承认,并在文献中得到了很好的记录。有研究表明,高达60%的精神分裂症患者使用非法药物。共有41名符合DSM-III-R精神分裂症和药物滥用或依赖标准的受试者被要求描述他们使用此类物质的原因、他们可能停止使用的原因以及这些物质的主观影响。据报道,毒品被用来增加快感、“兴奋”和减轻抑郁。然而,抑郁加重和阳性症状的主观影响也有报道。这些结果是在潜在治疗策略的背景下考虑的。
Abuse of and dependence on drugs, alcohol and other substances in schizophrenia are being increasingly recognized and well documented in the literature. It has been suggested that up to 60% of patients with schizophrenia use illicit drugs. A total of 41 subjects who fulfilled DSM-III-R criteria for schizophrenia and substance abuse or dependence were asked to describe their reasons for using such substances, the reasons why they might stop and the subjective effects of the substances. Drugs were reportedly used to increase pleasure, to 'get high' and to reduce depression. However, subjective effects of increased depression and positive symptoms were also reported. These results are considered in the context of potential treatment strategies.