Colonic transit time in constipated children: Does pediatric slow-transit constipation exist?
Colonic transit time in constipated children: Does pediatric slow-transit constipation exist?
复制标题
DOI：
10.1097/00005176-199610000-00007
复制
发表时间：
1996-10-01
影响因子：
2.9
通讯作者：
Taminiau, JAJM
中科院分区：
文献类型：
--
作者：
Benninga, MA;Buller, HA;Taminiau, JAJM
在成人中，慢传输型便秘是一种公认的便秘形式，检查时伴有腹痛和直肠排空。对这些患者（主要是女性）的标记物研究显示，所有结肠段的通过时间明显减慢。目前尚无针对便秘儿童的研究评估慢传输型便秘的存在。在一项前瞻性研究中，共有94名便秘儿科患者，63名男孩和31名女孩（中位年龄，8.0岁），使用不透射线标记物进行结肠传输时间测量，以评估传输模式。此外，在所有儿童中，使用氢呼吸（乳果糖）试验、肛门直肠测压和使用儿童行为检查表的行为研究进行口盲通过时间测量。根据便秘儿童总结肠通过时间（CTT）的上限（平均值+2 SD），我们将患者随机分为两组。CTT>100 h的儿童据说患有小儿慢传输型便秘（PSTC），而CTT患者
In adults, slow-transit constipation is a well-established form of constipation with abdominal pain and an empty rectum on examination. Marker studies in these patients, mainly women, show a markedly slowed transit time in all colonic segments. No studies in constipated children are available that assess the existence of slow-transit constipation. In a prospective study, a total of 94 referred constipated pediatric patients, 63 boys and 31 girls (median age, 8.0 years), underwent colonic-transit-time measurements using radioopaque markers to evaluate the pattern of transit. In addition, orocecal-transit-time measurements using the hydrogen breath (lactulose) test, anorectal manometry, and behavior studies using the Child Behavior Checklist were performed in all children. Based on the upper limit (mean + 2 SD) of total colonic transit time (CTT) in constipated children, we arbitrarily separated patients into two groups. Children with CTTs >100 h were said to have pediatric slow-transit constipation (PSTC), while patients with CTTs