Resistance Exercise-Induced Hypertrophy: A Potential Role for Rapamycin-Insensitive mTOR.
Resistance Exercise-Induced Hypertrophy: A Potential Role for Rapamycin-Insensitive mTOR.
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DOI：
10.1249/jes.0000000000000189
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发表时间：
2019-03
影响因子：
5.7
通讯作者：
R. Ogasawara;T. Jensen;C. Goodman;T. Hornberger
中科院分区：
文献类型：
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作者：
R. Ogasawara;T. Jensen;C. Goodman;T. Hornberger
雷帕霉素（mTOR）的机制靶点既能发挥雷帕霉素敏感信号事件，也能发挥雷帕霉素不敏感信号事件，而mTOR信号的雷帕霉素敏感成分已广泛参与阻力运动诱导骨骼肌肥大的途径。这篇综述探讨了mTOR信号的雷帕霉素不敏感成分也有助于这一高度重要的过程的假设。
The mechanistic target of rapamycin (mTOR) exerts both rapamycin-sensitive and rapamycin-insensitive signaling events, and the rapamycin-sensitive components of mTOR signaling have been widely implicated in the pathway through which resistance exercise induces skeletal muscle hypertrophy. This review explores the hypothesis that rapamycin-insensitive components of mTOR signaling also contribute to this highly important process.