POWER SPECTRUM AND INTRACRANIAL EEG PATTERNS AT SEIZURE ONSET IN PARTIAL EPILEPSY
POWER SPECTRUM AND INTRACRANIAL EEG PATTERNS AT SEIZURE ONSET IN PARTIAL EPILEPSY
复制标题
DOI：
10.1016/0013-4694(94)00286-t
复制
发表时间：
1995-05-01
期刊：
影响因子：
--
通讯作者：
POLKEY, CE
中科院分区：
文献类型：
--
作者：
ALARCON, G;BINNIE, CD;POLKEY, CE
在对15例接受手术评估的部分性癫痫患者进行术前评估时，使用脑内电极和硬膜下电极记录的癫痫发作起始的颅内脑电图模式与手术结果相关。对总共78次复杂部分性发作研究了发作起始时电极衰减事件、高频活动、夹杂慢活动的不规则尖波、棘 - 慢波活动以及节律性发作期转变的存在情况和分布。结合以下频谱变量（针对连续的1.28秒时段计算）的变化，对脑内和硬膜下记录的原始轨迹进行目测评估：振幅（一个频带内所有成分振幅之和）、活动度、移动性和复杂性。显示并评估了这些变量在发作前期和发作期的时间进程。该技术被证明对检测低振幅高频活动和细微的电极衰减事件是有效的。结论如下：(a)大多数患者（15例中的12例）显示出早期的电极衰减事件，有全身性的或局部的，主要涉及40Hz以下的频率；(b)发作起始时的全身性电极衰减事件并不意味着预后不良；(c)20 - 80Hz之间的局部高频活动与良好的预后相关。
Intracranial electroencephalographic patterns of seizure onset during preoperative assessment with intracerebral and subdural electrodes have been correlated with surgical outcome in 15 patients with partial epilepsy assessed for surgery. The presence and topography of electrodecremental events, high frequency activity, irregular sharp waves intermixed with slow activity, spike-wave activity and rhythmic ictal transformation at seizure onset were studied in a total of 78 complex partial seizures. Raw traces from intracerebral and subdural recordings were assessed visually in conjunction with changes in the following spectral variables (calculated for consecutive 1.28 sec epochs): amplitude (sum of amplitude of all components within a frequency band), activity, mobility, and complexity. The time course of these variables during preictal and ictal periods was displayed and assessed. This technique proved effective for detecting low-amplitude high-frequency activity and subtle electrodecremental events. It was concluded that: (a) most patients (12/15) showed early electrodecremental events, generalised or local, mainly involving frequencies below 40 Hz; (b) generalised electrodecremental events at onset did not imply poor outcome; (c) localised high-frequency activity, between 20 and 80 Hz, was associated with a good outcome.