Autoimmunity and glaucoma

Autoimmunity and glaucoma
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DOI:
10.1097/ijg.0b013e318156a592
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发表时间:
2008-01-01
影响因子:
2
通讯作者:
Pfeiffer, Norbert
Pfeiffer, Norbert
中科院分区:
医学3区
文献类型:
--
作者:
Grus, Franz H.;Joaehim, Stephanie C.;Pfeiffer, Norbert

文献摘要

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眼压升高并不能解释所有患者的青光眼,但有信息表明自身免疫机制可能与这种疾病有关。本综述试图揭示青光眼患者自身抗体谱的具体变化及其在青光眼中的可能作用。考虑到自然自身免疫的这些变化可以在不同的研究人群中一致地发现,它可能是青光眼检测的一个有前途的新工具。
Elevated intraocular pressure does not explain glaucoma in all patients, but there is information that autoimmune mechanisms may be involved in this disorder. This review attempts to reveal the findings about specific changes in autoantibody profiles in glaucoma patients and their possible role in glaucoma. Considering that these changes in natural autoimmunity can be found consistently among different study populations, it might be a promising new tool for glaucoma detection.