Relationship of household salt intake level with long-term all-cause and cardiovascular disease mortality in Japan: NIPPON DATA80
Relationship of household salt intake level with long-term all-cause and cardiovascular disease mortality in Japan: NIPPON DATA80
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DOI：
10.1038/s41440-019-0349-9
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发表时间：
2019-11
影响因子：
5.4
通讯作者：
A. Shima;N. Miyamatsu;K. Miura;N. Miyagawa;N. Okuda;K. Yoshita;A. Kadota;Harumitsu Suzuki;Keiko Kondo;T. Okamura;A. Okayama;H. Ueshima;for the Sessa Research Group
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文献类型：
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作者：
A. Shima;N. Miyamatsu;K. Miura;N. Miyagawa;N. Okuda;K. Yoshita;A. Kadota;Harumitsu Suzuki;Keiko Kondo;T. Okamura;A. Okayama;H. Ueshima;for the Sessa Research Group
在亚洲国家，盐摄入量的主要来源是在家中添加的调味料或食盐。然而，根据家庭单位对盐摄入量的不良影响知之甚少。我们调查了家庭盐摄入量与全因死亡率和心血管疾病（cvd）之间的关系。参与者包括8,702人（56%为女性），他们与他人同居，年龄在30-79岁之间，并于1980年参加了日本国家营养调查，随访24年。采用3天称重记录法评估家庭营养摄入量，其中记录了任何家庭成员消耗的所有食物和饮料。家庭盐摄入水平定义为每户家庭每1000千卡总能量摄入的盐摄入量(g)，其平均值为6.25 (2.02)g/1000千卡。在随访期间，有2,360人死亡（心血管疾病787例，冠心病168例，中风361例）。计算家庭盐摄入量增加2 g/1000 kcal的Cox比例风险比（HRs），并根据性别、年龄、体重指数、吸烟状况、饮酒状况、自我报告的工作强度、家庭钾摄入量、家庭饱和脂肪酸摄入量和家庭长链n-3多不饱和脂肪酸摄入量进行调整。全因死亡率的hr（95%可信区间）分别为1.07（1.02,1.12）、1.11（1.03,1.19）、1.25（1.08,1.44）和1.12（1.00,1.25）。家庭盐摄入量水平与全因、心血管疾病、冠心病和中风的长期风险显著相关
In Asian countries, a major source of salt intake is from seasoning or table salt added at home. However, little is known about the adverse effects of salt intake evaluated according to household unit. We investigated the relationship between household salt intake level and mortality from all-cause and cardiovascular diseases (CVDs). Participants included 8,702 individuals (56% women) who were living with someone else and who were aged 30–79 years and enrolled in the National Nutritional Survey of Japan in 1980 with a 24-year follow-up. Household nutrient intake was evaluated using a 3-day weighing record method in which all foods and beverages consumed by any of the household members were recorded. The household salt intake level was defined as the amount of salt consumed (g) per 1000 kcal of total energy intake in each household, and its average was 6.25 (2.02) g/1000 kcal. During the follow-up, there were 2,360 deaths (787 CVD, 168 coronary heart disease [CHD], and 361 stroke). Cox proportional hazard ratios (HRs) for an increment of 2 g/1000 kcal in household salt intake were calculated and adjusting for sex, age, body mass index, smoking status, alcohol consumption status, self-reported work exertion level, household potassium intake, household saturated fatty acid intake, and household long-chain n-3 polyunsaturated fatty acid intake. The HRs (95% confidence intervals) were 1.07 (1.02, 1.12) for all-cause mortality, 1.11 (1.03, 1.19) for CVD, 1.25 (1.08, 1.44) for CHD, and 1.12 (1.00, 1.25) for stroke. The household salt intake level was significantly associated with long-term risk of all-cause, CVD, CHD, and stroke