Brain Activation in Primary Motor and Somatosensory Cortices during Motor Imagery Correlates with Motor Imagery Ability in Stroke Patients.
Brain Activation in Primary Motor and Somatosensory Cortices during Motor Imagery Correlates with Motor Imagery Ability in Stroke Patients.
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DOI：
10.5402/2012/613595
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发表时间：
2012
期刊：
影响因子：
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通讯作者：
Butler AJ
中科院分区：
文献类型：
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作者：
Confalonieri L;Pagnoni G;Barsalou LW;Rajendra J;Eickhoff SB;Butler AJ
目标。虽然对健康受试者的研究表明运动执行和运动想象神经回路之间存在部分重叠，但很少有人研究中风偏瘫患者运动想象期间的大脑活动。这项工作的目的是检查一组中风患者的运动想象和执行之间的相似性。材料和方法。 11 名患者被要求在功能磁共振成像扫描期间使用拇指和食指在身体或精神上跟踪正弦波力目标来执行视觉运动跟踪任务。已进行 MIQ-RS 问卷调查。结果和结论。全脑分析证实了双侧前运动皮层、SMA 和对侧顶下小叶的运动想象和运动执行之间存在共享的神经基质。其他基于兴趣区域的分析揭示了动觉想象能力与区域 4p 和 3a 中大胆变化百分比之间的负相关性；较高的想象能力与运动想象期间初级感觉运动区域的负值和较低比例的大胆变化相关。
Aims. While studies on healthy subjects have shown a partial overlap between the motor execution and motor imagery neural circuits, few have investigated brain activity during motor imagery in stroke patients with hemiparesis. This work is aimed at examining similarities between motor imagery and execution in a group of stroke patients. Materials and Methods. Eleven patients were asked to perform a visuomotor tracking task by either physically or mentally tracking a sine wave force target using their thumb and index finger during fMRI scanning. MIQ-RS questionnaire has been administered. Results and Conclusion. Whole-brain analyses confirmed shared neural substrates between motor imagery and motor execution in bilateral premotor cortex, SMA, and in the contralesional inferior parietal lobule. Additional region of interest-based analyses revealed a negative correlation between kinaesthetic imagery ability and percentage BOLD change in areas 4p and 3a; higher imagery ability was associated with negative and lower percentage BOLD change in primary sensorimotor areas during motor imagery.