The Impact on Ovarian Reserve of Different Hemostasis Methods in Laparoscopic Cystectomy: A Systematic Review and Meta-analysis.

The Impact on Ovarian Reserve of Different Hemostasis Methods in Laparoscopic Cystectomy: A Systematic Review and Meta-analysis.
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DOI:
10.1055/s-0039-1692697
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发表时间:
2019-06
影响因子:
1.2
通讯作者:
Ribeiro, Paulo Ayroza
Ribeiro, Paulo Ayroza
中科院分区:
其他
文献类型:
--
作者:
Ferruzzi Baracat, Clara Micalli;Ayroza Abdalla-Ribeiro, Helizabet Salomao;da Cunha Araujo, Raquel Silveira;Bernando, Wanderley Marques;Ribeiro, Paulo Ayroza

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目的 本综述的目的是分析腹腔镜膀胱切除术中不同止血方法对卵巢储备功能的影响。数据来源 通过搜索电子数据库(MEDLINE、Embase、Cochrane、LILACS)和扫描文章参考列表来确定研究。研究选择方法 我们选择了临床试验,评估止血技术对超声表现良性的卵巢囊肿患者接受腹腔镜剥离术囊肿切除术的卵巢储备功能的影响。纳入的试验比较了不同的腹腔镜止血技术:缝合、双极电凝、超声能量和止血密封剂。评估的结果是血清抗苗勒氏管激素(AMH)水平和窦卵泡计数(AFC)。通过漏斗图评估发表偏倚的可能性。表格、整合和结果 评估了涉及 1,047 名患者的 12 项试验。在术后1、3、6、12个月评估血清AMH和AFC时,腹腔镜缝合优于双极电凝。在双极密封剂和止血密封剂的比较中,结果有利于止血剂的使用。超声波能量的使用并不优于双极能量的使用。结论 我们推荐腹腔镜膀胱切除术中缝合止血。
Objective The objective of this review was to analyze the impact on ovarian reserve of the different hemostatic methods used during laparoscopic cystectomy. Data Sources The studies were identified by searching electronic databases (MEDLINE, Embase, Cochrane, LILACS) and scanning reference lists of articles. Methods of Study Selection We selected clinical trials that assessed the influence of hemostatic techniques on ovarian reserve in patients with ovarian cysts with benign sonographic appearance submitted to laparoscopic cystectomy by stripping technique. The included trials compared different laparoscopic hemostatic techniques: suture, bipolar electrocoagulation, ultrasonic energy and hemostatic sealants. The outcomes evaluated were level of serum anti-Mullerian hormone (AMH) and antral follicle count (AFC). The possibility of publication bias was evaluated by funnel plots. Tabulation, Integration and Results Twelve trials involving 1,047 patients were evaluated. Laparoscopic suture was superior to bipolar coagulation when evaluating serum AMH and AFC, in the 1st, 3rd, 6th and 12th month after surgery. In the comparison between bipolar and hemostatic sealants, the results favored the use of hemostatic agents. The use of ultrasonic energy was not superior to the use of bipolar energy. Conclusion We recommend suture for hemostasis during laparoscopic cystectomy.
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