Polycystic Ovary Syndrome
Polycystic Ovary Syndrome
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DOI：
10.1016/j.cnur.2018.04.008
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发表时间：
2018-09-01
影响因子：
2
通讯作者：
Meier, Renate K.
中科院分区：
文献类型：
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作者：
Meier, Renate K.
多囊卵巢综合征（PCOS）是一种常见的内分泌疾病，以多毛症、无排卵和多囊卵巢为特征。通常与胰岛素抵抗、血脂异常和肥胖共存，它还具有发生心血管和代谢后遗症（包括糖尿病和代谢综合征）的重大风险。传统上，多囊卵巢综合症患者的治疗重点是缓解症状。本文回顾了 PCOS 的诊断标准，重点是按代谢特征对亚型进行分层。然后根据管理目标审查治疗方案：缓解高雄激素症状、调节月经和恢复生育能力。
Polycystic ovary syndrome (PCOS) is a commonly occurring endocrine disorder characterized by hirsutism, anovulation, and polycystic ovaries. Often comorbid with insulin resistance, dyslipidemia, and obesity, it also carries significant risk for the development of cardiovascular and metabolic sequelae, including diabetes and metabolic syndrome. Traditionally, the treatment of patients with PCOS has focused on relief of symptoms. Here, the criteria for the diagnosis of PCOS are reviewed, with an emphasis on the stratification of subtypes by metabolic features. Then treatment options are reviewed according to the management goal: relief of hyperandrogenic symptoms, regulation of menstruation, and restoration of fertility.