Asymptotics of a Brownian ratchet for protein translocation
Asymptotics of a Brownian ratchet for protein translocation
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蛋白质易位的布朗棘轮渐进
DOI:
10.1016/j.spa.2010.01.018
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发表时间:
2009
影响因子:
1.4
通讯作者:
P. Pfaffelhuber
中科院分区:
文献类型:
--
作者:
A. Depperschmidt;P. Pfaffelhuber
Protein translocation in cells has been modelled by Brownian ratchets. In such models, the protein diffuses through a nanopore. On one side of the pore, ratcheting molecules bind to the protein and hinder it to diffuse out of the pore. We study a Brownian ratchet by means of a reflected Brownian motion [Formula: see text] with a changing reflection point [Formula: see text] . The rate of change of Rtis γ(Xt−Rt) and the new reflection boundary is distributed uniformly between Rt−and Xt. The asymptotic speed of the ratchet scales with γ1/3and the asymptotic variance is independent of γ.
影响因子:
5.6
作者:
Liebermeister, W;Rapoport, TA;Heinrich, R
通讯作者:
Heinrich, R