Bronchial artery and systemic artery embolization in the management of primary lung cancer patients with hemoptysis
Bronchial artery and systemic artery embolization in the management of primary lung cancer patients with hemoptysis
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DOI：
10.1007/s00270-007-9034-5
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发表时间：
2007-07-01
影响因子：
2.9
通讯作者：
Lee, Jin Soo
中科院分区：
文献类型：
--
作者：
Park, Hong Suk;Kim, Young Il;Lee, Jin Soo
目的评价动脉栓塞治疗肺癌咯血患者的安全性和有效性。2002年4月至2005年3月间，19例原发性肺癌咯血患者行支气管动脉及全身动脉栓塞术。男性17例，女性2例，平均年龄59岁。组织学分析显示10例为鳞状细胞癌，9例为低分化腺癌。咯血量为：8例24小时内出血25- 50ml， 6例反复出现带血痰，5例24小时出血100ml及以上。栓塞采用超选择性技术，使用微导管和聚乙烯醇颗粒闭塞受影响的血管。动脉栓塞术在技术上是成功的，在临床上是成功的15例（79%）。平均栓塞动脉数为1.2条。支气管动脉造影显示染色（所有患者），动脉扩张或血管增生（10例），支气管肺分流（6例）。复发率为33%(5/15)，存活11例，平均随访时间为148天（30-349天）。动脉栓塞治疗原发性肺癌患者咯血是一种有效、安全的治疗方式，尽管血管造影显示血管变化很细微。
To assess the safety and effectiveness of arterial embolization in lung cancer patients with hemoptysis.Nineteen primary lung cancer patients with hemoptysis underwent bronchial artery and systemic artery embolization from April 2002 to March 2005. There were 17 men and 2 women, with a mean age of 59 years. Histologic analysis revealed squamous cell carcinoma in 10 patients and poorly differentiated adenocarcinoma in 9 patients. The amount of hemoptysis was bleeding of 25-50 ml within 24 hr in 8 patients, recurrent blood-tinged sputum in 6, and bleeding of 100 ml or more per 24 hr in 5. Embolization was done with a superselective technique using a microcatheter and polyvinyl alcohol particles to occlude the affected vessels.Arterial embolization was technically successful in all patients and clinically successful in 15 patients (79%). The average number of arteries embolized was 1.2. Bronchial arteriography revealed staining (all patients), dilatation of the artery or hypervascularity (10 patients), and bronchopulmonary shunt (6 patients). The recurrence rate was 33% (5/15) and 11 patients were alive with a mean follow-up time of 148 days (30-349 days).Arterial embolotherapy for hemoptysis in patients with primary lung cancer is an effective, safe therapeutic modality despite the fact the vascular changes are subtle on angiography.